Detailed information NTG1124135

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: EL309_RS10580
• Genome accession: NZ_LR134533
• Coordinates: 2227804..2228937 (-)
• Length: 377 a.a.
• NCBI ID: WP_004285269.1
• Uniprot ID: -
• Organism: Neisseria weaveri strain NCTC12742
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2222804..2233937

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL309_RS10570 (NCTC12742_02092)	gyrA	2222927..2225674 (+)	2748	WP_004283331.1	DNA gyrase subunit A	-
EL309_RS10575 (NCTC12742_02093)	dld	2226036..2227727 (+)	1692	WP_004285270.1	D-lactate dehydrogenase	-
EL309_RS10580 (NCTC12742_02094)	pilU	2227804..2228937 (-)	1134	WP_004285269.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
EL309_RS10585 (NCTC12742_02095)	-	2229111..2229830 (+)	720	WP_004285268.1	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	-
EL309_RS10590 (NCTC12742_02096)	recD	2229886..2231643 (+)	1758	WP_004285267.1	exodeoxyribonuclease V subunit alpha	Machinery gene
EL309_RS10595 (NCTC12742_02097)	ung	2231784..2232443 (+)	660	WP_004285265.1	uracil-DNA glycosylase	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42152.19 Da
• Isoelectric Point: 6.4308

>NTDB_id=1124135 EL309_RS10580 WP_004285269.1 2227804..2228937(-) (pilU) [Neisseria weaveri strain NCTC12742]
MNHPNTSLPAKEELYSWLKHLNKYKGSDLFVTAKFPPAMKLDGKITPISDTPLDAERCMEMAFSIMTPKQIEEFTQTNEC
NFAISLPNTSRFRVNAMVQRGATALVFRSITSNIPSFDTLNLPPVLKDIAMQKRGLVIFVGGTGSGKSTSLASMIDFRNE
NSHDHIITIEDPIEFVHEHKNCIVTQREIGVDTENWHAALKNTLRQAPDVILIGEIRDRETMDYAIAFAETGHLCMATLH
ANSTNQALDRIINFFPEERRVQLLTDLSLNLQAFVSQRLIPREGGRGRVAAAEILMNSPLIAELILKGDVHGIKEVMKKS
TASGMQTFDQALYNLYETGQISFQDAIKNADSAHDLRTDIQLRSRRAQTAGPDLELI

Nucleotide

• Length: 1134 bp

>NTDB_id=1124135 EL309_RS10580 WP_004285269.1 2227804..2228937(-) (pilU) [Neisseria weaveri strain NCTC12742]
ATGAACCATCCTAATACGTCTTTACCCGCAAAAGAAGAACTCTATTCTTGGCTGAAACACCTGAATAAATACAAAGGTTC
CGATTTATTCGTGACCGCCAAATTCCCGCCCGCCATGAAGCTGGACGGCAAAATCACCCCCATCAGCGATACGCCGCTGG
ACGCGGAACGCTGCATGGAAATGGCGTTTTCCATCATGACGCCCAAACAGATCGAAGAATTCACCCAAACCAACGAATGC
AACTTCGCCATCAGCCTGCCGAATACCAGCCGCTTCCGCGTCAATGCTATGGTGCAAAGAGGCGCAACCGCTTTGGTTTT
CCGCTCAATCACGTCCAACATTCCTTCGTTCGACACGCTCAACCTGCCGCCCGTATTAAAAGACATCGCCATGCAGAAAC
GCGGCTTGGTGATTTTTGTCGGCGGCACCGGCTCGGGTAAGTCCACGTCGCTGGCTTCCATGATCGACTTCCGCAATGAA
AACAGCCACGACCACATCATCACCATCGAAGACCCGATCGAATTTGTCCACGAACACAAAAACTGTATCGTTACCCAACG
CGAAATCGGCGTAGACACCGAAAACTGGCATGCCGCATTGAAAAACACCCTGCGTCAAGCACCCGATGTGATTCTGATCG
GCGAAATCCGCGACCGCGAAACCATGGACTATGCCATTGCCTTCGCCGAAACCGGCCACTTGTGTATGGCAACGCTGCAC
GCCAACAGCACCAACCAGGCTTTGGACCGCATTATCAACTTCTTCCCCGAAGAGCGCCGCGTCCAACTGCTCACCGACCT
GTCGCTCAACCTGCAAGCCTTCGTATCCCAACGCCTGATTCCGCGCGAAGGCGGCAGAGGCCGTGTTGCCGCAGCGGAAA
TCCTGATGAATTCTCCGCTCATTGCCGAACTGATTCTGAAAGGCGACGTACACGGGATTAAAGAAGTGATGAAAAAATCC
ACCGCATCCGGTATGCAGACATTCGACCAAGCCTTATACAACCTGTATGAAACCGGTCAAATCAGCTTCCAAGATGCCAT
CAAAAACGCCGACTCCGCACACGATTTGCGCACCGACATCCAATTGCGCAGCCGCCGCGCCCAAACCGCCGGCCCGGATT
TGGAATTGATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (41-258)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Pseudomonas stutzeri DSM 10701	59.659	93.369	0.557
pilU	Acinetobacter baylyi ADP1	57.349	92.042	0.528
pilU	Vibrio cholerae strain A1552	50.975	95.225	0.485
pilT	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	43.827	85.942	0.377
pilT	Legionella pneumophila strain Lp02	44.062	84.881	0.374
pilT	Legionella pneumophila strain ERS1305867	44.062	84.881	0.374
pilT	Acinetobacter baylyi ADP1	42.378	87.003	0.369
pilT	Acinetobacter baumannii strain A118	42.593	85.942	0.366
pilT	Acinetobacter nosocomialis M2	42.593	85.942	0.366
pilT	Acinetobacter baumannii D1279779	42.593	85.942	0.366
pilT	Neisseria meningitidis 8013	40.896	88.859	0.363
pilT	Pseudomonas aeruginosa PAK	41.768	87.003	0.363