Detailed information NTG1116228

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: EQB41_RS10640
• Genome accession: NZ_LR129840
• Coordinates: 1957533..1957859 (-)
• Length: 108 a.a.
• NCBI ID: WP_050237957.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4496 isolate 4496
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1952533..1962859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB41_RS10600	rnpA	1952550..1952921 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQB41_RS12675	-	1952938..1953069 (-)	132	WP_000768904.1	hypothetical protein	-
EQB41_RS10605	-	1953070..1954260 (-)	1191	WP_000167765.1	acetate kinase	-
EQB41_RS10610	comYH	1954311..1955264 (-)	954	WP_050237953.1	class I SAM-dependent methyltransferase	Machinery gene
EQB41_RS10615	-	1955325..1955919 (-)	595	Protein_1980	class I SAM-dependent methyltransferase	-
EQB41_RS10620	comGG/cglG	1956056..1956469 (-)	414	WP_050237955.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQB41_RS10625	comGF/cglF	1956447..1956908 (-)	462	WP_127820861.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQB41_RS10630	comGE/cglE	1956871..1957173 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQB41_RS10635	comGD/cglD	1957136..1957540 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQB41_RS10640	comGC/cglC	1957533..1957859 (-)	327	WP_050237957.1	comG operon protein ComGC	Machinery gene
EQB41_RS10645	comGB/cglB	1957861..1958877 (-)	1017	WP_127820862.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQB41_RS10650	comGA/cglA/cilD	1958825..1959766 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
EQB41_RS10655	-	1959842..1960207 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQB41_RS10660	-	1960358..1961416 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
EQB41_RS10665	nagA	1961579..1962730 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12212.39 Da
• Isoelectric Point: 10.1432

>NTDB_id=1116228 EQB41_RS10640 WP_050237957.1 1957533..1957859(-) (comGC/cglC) [Streptococcus pneumoniae strain 4496 isolate 4496]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=1116228 EQB41_RS10640 WP_050237957.1 1957533..1957859(-) (comGC/cglC) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae Rx1	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae D39	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae R6	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae TIGR4	95.37	100	0.954
comGC/cglC	Streptococcus mitis SK321	94.444	100	0.944
comGC/cglC	Streptococcus mitis NCTC 12261	91.837	90.741	0.833
comYC	Streptococcus gordonii str. Challis substr. CH1	66.019	95.37	0.63
comYC	Streptococcus mutans UA140	60.784	94.444	0.574
comYC	Streptococcus mutans UA159	60.784	94.444	0.574
comYC	Streptococcus suis isolate S10	64.773	81.481	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comGC	Staphylococcus aureus MW2	48.837	79.63	0.389
comGC	Staphylococcus aureus N315	48.837	79.63	0.389