Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   AAA996_RS09790 Genome accession   NZ_AP028606
Coordinates   1897375..1897701 (-) Length   108 a.a.
NCBI ID   WP_000738626.1    Uniprot ID   Q8DN88
Organism   Streptococcus pneumoniae strain Sep1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1892375..1902701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS09745 (TKY121773_18960) rnpA 1892392..1892763 (-) 372 WP_000739246.1 ribonuclease P protein component -
  AAA996_RS09750 - 1892780..1892911 (-) 132 WP_000768904.1 hypothetical protein -
  AAA996_RS09755 (TKY121773_18970) - 1892912..1894102 (-) 1191 WP_000167766.1 acetate kinase -
  AAA996_RS09760 (TKY121773_18980) comYH 1894153..1895106 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  AAA996_RS09765 - 1895167..1895761 (-) 595 Protein_1898 methyltransferase domain-containing protein -
  AAA996_RS09770 (TKY121773_19010) comGG/cglG 1895898..1896311 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAA996_RS09775 (TKY121773_19020) comGF/cglF 1896289..1896750 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAA996_RS09780 (TKY121773_19030) comGE/cglE 1896713..1897015 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAA996_RS09785 (TKY121773_19040) comGD/cglD 1896978..1897382 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAA996_RS09790 (TKY121773_19050) comGC/cglC 1897375..1897701 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  AAA996_RS09795 (TKY121773_19060) comGB/cglB 1897703..1898719 (-) 1017 WP_078375398.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAA996_RS09800 (TKY121773_19070) comGA/cglA/cilD 1898667..1899608 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  AAA996_RS09805 (TKY121773_19080) - 1899684..1900049 (-) 366 WP_000286415.1 DUF1033 family protein -
  AAA996_RS09810 (TKY121773_19090) - 1900200..1901258 (-) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  AAA996_RS09815 (TKY121773_19100) nagA 1901421..1902572 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12200.38 Da        Isoelectric Point: 10.1877

>NTDB_id=106234 AAA996_RS09790 WP_000738626.1 1897375..1897701(-) (comGC/cglC) [Streptococcus pneumoniae strain Sep1]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=106234 AAA996_RS09790 WP_000738626.1 1897375..1897701(-) (comGC/cglC) [Streptococcus pneumoniae strain Sep1]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6Y1H

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

100

100

1
  comGC/cglC Streptococcus pneumoniae D39

100

100

1
  comGC/cglC Streptococcus pneumoniae R6

100

100

1
  comGC/cglC Streptococcus pneumoniae TIGR4

99.074

100

0.991
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment