Detailed information NTG0106231

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AAA996_RS09775
• Genome accession: NZ_AP028606
• Coordinates: 1896289..1896750 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1891289..1901750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA996_RS09740 (TKY121773_18950)	-	1891593..1892417 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
AAA996_RS09745 (TKY121773_18960)	rnpA	1892392..1892763 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AAA996_RS09750	-	1892780..1892911 (-)	132	WP_000768904.1	hypothetical protein	-
AAA996_RS09755 (TKY121773_18970)	-	1892912..1894102 (-)	1191	WP_000167766.1	acetate kinase	-
AAA996_RS09760 (TKY121773_18980)	comYH	1894153..1895106 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
AAA996_RS09765	-	1895167..1895761 (-)	595	Protein_1898	methyltransferase domain-containing protein	-
AAA996_RS09770 (TKY121773_19010)	comGG/cglG	1895898..1896311 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
AAA996_RS09775 (TKY121773_19020)	comGF/cglF	1896289..1896750 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
AAA996_RS09780 (TKY121773_19030)	comGE/cglE	1896713..1897015 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AAA996_RS09785 (TKY121773_19040)	comGD/cglD	1896978..1897382 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
AAA996_RS09790 (TKY121773_19050)	comGC/cglC	1897375..1897701 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
AAA996_RS09795 (TKY121773_19060)	comGB/cglB	1897703..1898719 (-)	1017	WP_078375398.1	competence type IV pilus assembly protein ComGB	Machinery gene
AAA996_RS09800 (TKY121773_19070)	comGA/cglA/cilD	1898667..1899608 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
AAA996_RS09805 (TKY121773_19080)	-	1899684..1900049 (-)	366	WP_000286415.1	DUF1033 family protein	-
AAA996_RS09810 (TKY121773_19090)	-	1900200..1901258 (-)	1059	WP_000649473.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=106231 AAA996_RS09775 WP_000250542.1 1896289..1896750(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep1]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=106231 AAA996_RS09775 WP_000250542.1 1896289..1896750(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep1]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909