Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ABKA15_RS01270 Genome accession   NZ_CP157941
Coordinates   244933..245874 (+) Length   313 a.a.
NCBI ID   WP_049513218.1    Uniprot ID   A0A7L8W3A5
Organism   Streptococcus sp. KHUD_010     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 239933..250874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS01245 (ABKA15_01240) - 241082..241765 (+) 684 WP_049513227.1 CHAP domain-containing protein -
  ABKA15_RS01250 (ABKA15_01245) - 241915..242415 (+) 501 Protein_243 aromatic acid exporter family protein -
  ABKA15_RS01255 (ABKA15_01250) - 242577..242957 (+) 381 WP_350015362.1 MerR family transcriptional regulator -
  ABKA15_RS01260 (ABKA15_01255) glnA 242968..244310 (+) 1343 Protein_245 type I glutamate--ammonia ligase -
  ABKA15_RS01265 (ABKA15_01260) - 244498..244863 (+) 366 WP_049507022.1 DUF1033 family protein -
  ABKA15_RS01270 (ABKA15_01265) comYA 244933..245874 (+) 942 WP_049513218.1 competence type IV pilus ATPase ComGA Machinery gene
  ABKA15_RS01275 (ABKA15_01270) comYB 245816..246838 (+) 1023 WP_185952230.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABKA15_RS01280 (ABKA15_01275) comYC 246835..247152 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ABKA15_RS01285 (ABKA15_01280) comYD 247112..247540 (+) 429 WP_049507639.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABKA15_RS01290 (ABKA15_01285) comGE/cglE 247512..247805 (+) 294 WP_049513214.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABKA15_RS01295 (ABKA15_01290) comGF/cglF 247789..248226 (+) 438 WP_049513212.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABKA15_RS01300 (ABKA15_01295) comGG 248207..248533 (+) 327 WP_264340993.1 competence type IV pilus minor pilin ComGG -
  ABKA15_RS01305 (ABKA15_01300) comYH 248605..249558 (+) 954 WP_049513210.1 class I SAM-dependent methyltransferase Machinery gene
  ABKA15_RS01310 (ABKA15_01305) - 249605..250804 (+) 1200 WP_049513208.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35754.98 Da        Isoelectric Point: 6.0540

>NTDB_id=1009085 ABKA15_RS01270 WP_049513218.1 244933..245874(+) (comYA) [Streptococcus sp. KHUD_010]
MVQNIAQAIICQAKEEQAQDIYVVPKENMYELYMRIGDERRFIQQYAFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKTSLRLSTVGDYRGYESLVIRLLHDEESELKFWFAQIPELKECFKQRGLYLFSGPVGSGKTTLMHQLAQERFAGQQ
IMSIEDPVEIKQPSMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDGETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEADLKIVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1009085 ABKA15_RS01270 WP_049513218.1 244933..245874(+) (comYA) [Streptococcus sp. KHUD_010]
ATGGTTCAAAATATTGCACAGGCTATTATTTGCCAAGCTAAGGAAGAACAGGCACAGGATATTTACGTTGTTCCAAAGGA
GAATATGTATGAGCTATACATGCGAATTGGCGATGAACGGCGTTTTATCCAACAGTATGCATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTCAAGTTTACCGCTGGAATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGATAAGAAAACGTCATTACGACTGTCAACAGTAGGGGATTATCGTGGATATGAAAGTCTGGTGATTCGTTTATT
ACATGATGAAGAGTCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAATGCTTCAAACAACGAGGGCTTT
ATCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACGACTCTCATGCACCAACTTGCCCAAGAGCGCTTTGCTGGTCAACAA
ATCATGTCCATTGAAGACCCTGTTGAAATCAAGCAGCCTAGCATGTTACAGTTGCAATTGAATGAAGCGATTGGTTTGAC
TTATGAAAATTTGATTAAACTTTCTCTACGGCACCGACCGGATTTGCTAATCATCGGAGAAATTCGAGATGGGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGTTGGAATTGGGAGTGACAGAAGCCGATCTGAAAATTGTCTTGCAAGGGATTTGTTACCAACGTTTAATTGC
AAAAGGAGGAATAGTGGATTTTGTCAGTGAAAAGTATCAAGAACACGAGCCCATCGACTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAACAAGCAGAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W3A5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.903

99.042

0.821
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.019

99.361

0.537
  comGA Latilactobacillus sakei subsp. sakei 23K

43.629

82.748

0.361

Multiple sequence alignment