Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ABKA15_RS01290 Genome accession   NZ_CP157941
Coordinates   247512..247805 (+) Length   97 a.a.
NCBI ID   WP_049513214.1    Uniprot ID   A0AAU7PY72
Organism   Streptococcus sp. KHUD_010     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 242512..252805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS01255 (ABKA15_01250) - 242577..242957 (+) 381 WP_350015362.1 MerR family transcriptional regulator -
  ABKA15_RS01260 (ABKA15_01255) glnA 242968..244310 (+) 1343 Protein_245 type I glutamate--ammonia ligase -
  ABKA15_RS01265 (ABKA15_01260) - 244498..244863 (+) 366 WP_049507022.1 DUF1033 family protein -
  ABKA15_RS01270 (ABKA15_01265) comYA 244933..245874 (+) 942 WP_049513218.1 competence type IV pilus ATPase ComGA Machinery gene
  ABKA15_RS01275 (ABKA15_01270) comYB 245816..246838 (+) 1023 WP_185952230.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABKA15_RS01280 (ABKA15_01275) comYC 246835..247152 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ABKA15_RS01285 (ABKA15_01280) comYD 247112..247540 (+) 429 WP_049507639.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABKA15_RS01290 (ABKA15_01285) comGE/cglE 247512..247805 (+) 294 WP_049513214.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABKA15_RS01295 (ABKA15_01290) comGF/cglF 247789..248226 (+) 438 WP_049513212.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABKA15_RS01300 (ABKA15_01295) comGG 248207..248533 (+) 327 WP_264340993.1 competence type IV pilus minor pilin ComGG -
  ABKA15_RS01305 (ABKA15_01300) comYH 248605..249558 (+) 954 WP_049513210.1 class I SAM-dependent methyltransferase Machinery gene
  ABKA15_RS01310 (ABKA15_01305) - 249605..250804 (+) 1200 WP_049513208.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10895.82 Da        Isoelectric Point: 9.8140

>NTDB_id=1009089 ABKA15_RS01290 WP_049513214.1 247512..247805(+) (comGE/cglE) [Streptococcus sp. KHUD_010]
MENLRKQHVKGTILLEALLALAIFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIEVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1009089 ABKA15_RS01290 WP_049513214.1 247512..247805(+) (comGE/cglE) [Streptococcus sp. KHUD_010]
ATGGAAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTGAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

44.444

100

0.454
  comYE Streptococcus mutans UA159

44.444

100

0.454

Multiple sequence alignment