Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ABKA15_RS01275 Genome accession   NZ_CP157941
Coordinates   245816..246838 (+) Length   340 a.a.
NCBI ID   WP_185952230.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_010     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 240816..251838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS01245 (ABKA15_01240) - 241082..241765 (+) 684 WP_049513227.1 CHAP domain-containing protein -
  ABKA15_RS01250 (ABKA15_01245) - 241915..242415 (+) 501 Protein_243 aromatic acid exporter family protein -
  ABKA15_RS01255 (ABKA15_01250) - 242577..242957 (+) 381 WP_350015362.1 MerR family transcriptional regulator -
  ABKA15_RS01260 (ABKA15_01255) glnA 242968..244310 (+) 1343 Protein_245 type I glutamate--ammonia ligase -
  ABKA15_RS01265 (ABKA15_01260) - 244498..244863 (+) 366 WP_049507022.1 DUF1033 family protein -
  ABKA15_RS01270 (ABKA15_01265) comYA 244933..245874 (+) 942 WP_049513218.1 competence type IV pilus ATPase ComGA Machinery gene
  ABKA15_RS01275 (ABKA15_01270) comYB 245816..246838 (+) 1023 WP_185952230.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABKA15_RS01280 (ABKA15_01275) comYC 246835..247152 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ABKA15_RS01285 (ABKA15_01280) comYD 247112..247540 (+) 429 WP_049507639.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABKA15_RS01290 (ABKA15_01285) comGE/cglE 247512..247805 (+) 294 WP_049513214.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABKA15_RS01295 (ABKA15_01290) comGF/cglF 247789..248226 (+) 438 WP_049513212.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABKA15_RS01300 (ABKA15_01295) comGG 248207..248533 (+) 327 WP_264340993.1 competence type IV pilus minor pilin ComGG -
  ABKA15_RS01305 (ABKA15_01300) comYH 248605..249558 (+) 954 WP_049513210.1 class I SAM-dependent methyltransferase Machinery gene
  ABKA15_RS01310 (ABKA15_01305) - 249605..250804 (+) 1200 WP_049513208.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39057.12 Da        Isoelectric Point: 9.6570

>NTDB_id=1009086 ABKA15_RS01275 WP_185952230.1 245816..246838(+) (comYB) [Streptococcus sp. KHUD_010]
MQQDISILNKQKRKKLSTVKQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEEVYVDRMKEGLSTGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENVSKIKKKLVEVATYPFILFVFLIFIILGLRNYLLPQLDRQNVATQIISNLPQ
IFLGSLGVVFVLLAIGFYWFQKSSKIAAFRLLARLPFFGAFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQRVKTYPFFKKELGLMIEYGEVKSRLGRELEVYAQKTWETFFKCVHQAMNVIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=1009086 ABKA15_RS01275 WP_185952230.1 245816..246838(+) (comYB) [Streptococcus sp. KHUD_010]
ATGCAGCAGGACATATCAATCTTGAACAAGCAGAAGCGGAAAAAATTATCCACAGTTAAGCAGAAAAAGGTCGTAGAGTT
ACTGAATAATCTTTTTTCTAGTGGCTTTCATTTGGCAGAAATTATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG
TCTATGTGGACAGGATGAAAGAGGGGTTGTCAACAGGAAAGCCTTTTTCGGACATCATGGCAAGCTTAGGTTTTTCAGAT
AATGTAGTAACACAACTTTCACTGGCAGAATTACACGGAAATCTCTCACTCAGCCTGAGTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAATTAAGAAAAAGTTGGTTGAAGTGGCGACTTATCCCTTTATTTTGTTTGTTTTTTTGATATTCATTA
TACTGGGATTACGTAATTATTTACTCCCGCAACTCGATCGTCAAAATGTAGCAACGCAGATTATCAGTAATTTGCCGCAA
ATTTTTCTGGGTTCATTAGGAGTAGTCTTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTCAAAAAAGCTCAAAAATAGC
AGCATTTCGTTTGTTAGCTCGCCTTCCTTTTTTTGGCGCTTTTATTCAAACGTATTTGACAGCTTATTATGCGAGAGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTTAGTCAGATTTTTCAGATGATGCAAGGACAACGCTCTGCTATGTTTCAA
GAAATTGGGAAAGATTTAGAAGTTGCACTGCAAAATGGTCAGGAATTTTCGCAAAGGGTTAAAACATATCCATTTTTTAA
AAAGGAATTGGGCTTGATGATTGAATACGGCGAAGTGAAGTCTAGATTGGGGCGTGAATTAGAAGTTTATGCTCAAAAAA
CATGGGAGACTTTTTTTAAATGTGTTCACCAGGCGATGAATGTCATTCAACCACTAGTGTTTGTCTTTGTGGCTTTAATG
ATTGTATTGTTGTATGCAGCCATGCTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

70

100

0.7
  comGB/cglB Streptococcus mitis NCTC 12261

67.463

98.529

0.665
  comGB/cglB Streptococcus mitis SK321

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae TIGR4

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae R6

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae Rx1

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae D39

66.866

98.529

0.659
  comYB Streptococcus mutans UA159

59.942

100

0.603
  comYB Streptococcus mutans UA140

59.649

100

0.6
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

99.118

0.503

Multiple sequence alignment