Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 347842..348380 Replicon chromosome
Accession NZ_CP024868
Organism Vibrio cholerae strain A1552

Toxin (Protein)


Gene name parE Uniprot ID Q9KMJ0
Locus tag VCA1552_RS16035 Protein ID WP_000802136.1
Coordinates 347842..348141 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID P58093
Locus tag VCA1552_RS16040 Protein ID WP_001107719.1
Coordinates 348138..348380 (-) Length 81 a.a.

Genomic Context

VCA1552_RS15985VCA1552_RS15990VCA1552_RS15995VCA1552_RS16000VCA1552_RS16005VCA1552_RS16010VCA1552_RS16025VCA1552_RS16030VCA1552_RS16050VCA1552_RS16055VCA1552_RS16065VCA1552_RS16075VCA1552_RS16085VCA1552_RS16090VCA1552_RS16095VCA1552_RS16035VCA1552_RS16040
Location: 343777..343959 (183 bp)
Type: Others
Protein ID: WP_000923182.1
Location: 344159..344632 (474 bp)
Type: Others
Protein ID: WP_001161076.1
Location: 344629..344739 (111 bp)
Type: Others
Protein ID: WP_071908312.1
Location: 344781..345407 (627 bp)
Type: Others
Protein ID: WP_000365424.1
Location: 345530..346228 (699 bp)
Type: Others
Protein ID: WP_001890502.1
Location: 346232..346348 (117 bp)
Type: Others
Protein ID: WP_071908339.1
Location: 346926..347105 (180 bp)
Type: Others
Protein ID: WP_001883058.1
Location: 347319..347714 (396 bp)
Type: Others
Protein ID: WP_000870857.1
Location: 348609..349187 (579 bp)
Type: Others
Protein ID: WP_000110120.1
Location: 349191..349301 (111 bp)
Type: Others
Protein ID: WP_071908313.1
Location: 349725..350408 (684 bp)
Type: Others
Protein ID: WP_000877436.1
Location: 350622..350888 (267 bp)
Type: Others
Protein ID: WP_000937852.1
Location: 351043..351642 (600 bp)
Type: Others
Protein ID: WP_000429495.1
Location: 351923..352858 (936 bp)
Type: Others
Protein ID: WP_000051985.1
Location: 352824..352964 (141 bp)
Type: Others
Protein ID: WP_001883049.1
Location: 347842..348141 (300 bp)
Type: Toxin
Protein ID: WP_000802136.1
Location: 348138..348380 (243 bp)
Type: Antitoxin
Protein ID: WP_001107719.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VCA1552_RS15985343777..343959+183WP_000923182.1DUF645 family protein-
VCA1552_RS15990344159..344632+474WP_001161076.1GrpB family protein-
VCA1552_RS15995344629..344739+111WP_071908312.1DUF3265 domain-containing protein-
VCA1552_RS16000344781..345407+627WP_000365424.1LysE family translocator-
VCA1552_RS16005345530..346228+699WP_001890502.1hypothetical protein-
VCA1552_RS16010346232..346348+117WP_071908339.1DUF3265 domain-containing protein-
VCA1552_RS16025346926..347105+180WP_001883058.1DUF645 family protein-
VCA1552_RS16030347319..347714+396WP_000870857.1DUF3465 domain-containing protein-
VCA1552_RS16035347842..348141-300WP_000802136.1type II toxin-antitoxin system RelE/ParE family toxinToxin
VCA1552_RS16040348138..348380-243WP_001107719.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
VCA1552_RS16050348609..349187+579WP_000110120.1hypothetical protein-
VCA1552_RS16055349191..349301+111WP_071908313.1DUF3265 domain-containing protein-
VCA1552_RS16065349725..350408+684WP_000877436.1hypothetical protein-
VCA1552_RS16075350622..350888+267WP_000937852.1hypothetical protein-
VCA1552_RS16085351043..351642+600WP_000429495.1hypothetical protein-
VCA1552_RS16090351923..352858+936WP_000051985.1restriction endonuclease-
VCA1552_RS16095352824..352964+141WP_001883049.1DUF3265 domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandcatB9-304717..433978129261
insideIntegron--309797..433602123805


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11589.29 Da        Isoelectric Point: 9.9232

>T88992 WP_000802136.1 NZ_CP024868:c348141-347842 [Vibrio cholerae]
MKPFNLTVAAKADLRDIALFTQRRWGKEQRNVYLKQFDDSFWLLAENPDIGKSCDEIREGYRKFPQGSHVIFYQQTGSQQ
IRVIRILHKSMDVNPIFGA

Download         Length: 300 bp

>T88992 NZ_CP024868:c348141-347842 [Vibrio cholerae]
ATGAAACCATTTAATCTTACCGTCGCCGCCAAAGCCGATTTACGTGATATTGCTTTATTCACTCAACGACGCTGGGGAAA
AGAGCAGCGAAATGTTTATTTAAAGCAATTCGATGATTCCTTTTGGCTTTTAGCGGAAAATCCCGACATTGGTAAATCAT
GCGATGAAATCCGAGAGGGATACAGAAAATTTCCCCAAGGGAGTCACGTCATCTTTTATCAGCAAACCGGCAGCCAACAA
ATCAGGGTGATCCGAATTCTTCATAAGAGCATGGATGTGAACCCAATATTCGGCGCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8964.84 Da        Isoelectric Point: 4.1677

>AT88992 WP_001107719.1 NZ_CP024868:c348380-348138 [Vibrio cholerae]
MAKNTSITLGEHFDGFITSQIQSGRYGSASEVIRSALRLLENQETKLQSLRQLLIEGEQSGDADYDLDSFINELDSENIR

Download         Length: 243 bp

>AT88992 NZ_CP024868:c348380-348138 [Vibrio cholerae]
ATGGCTAAAAATACAAGTATCACTCTTGGTGAACACTTCGATGGCTTTATTACAAGCCAAATACAAAGTGGGCGTTACGG
CTCAGCAAGTGAAGTCATTCGCTCTGCGCTACGTCTACTCGAAAACCAAGAAACCAAACTACAGTCACTCCGTCAACTAC
TTATTGAAGGAGAGCAAAGTGGTGACGCTGATTATGACCTTGATAGCTTCATCAATGAACTCGATAGTGAAAACATTCGA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
PDB7R5A

Antitoxin

Loading, please wait
Source
ID
Structure
PDB7R5A
PDB7B22
AlphaFold DBA0A151JFU4

References