Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 427083..427611 Replicon chromosome
Accession NZ_CP013306
Organism Vibrio cholerae strain CRC1106

Toxin (Protein)


Gene name relE Uniprot ID H9L4R3
Locus tag ASZ81_RS16760 Protein ID WP_000221352.1
Coordinates 427083..427373 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H9L4T4
Locus tag ASZ81_RS16765 Protein ID WP_000213183.1
Coordinates 427363..427611 (-) Length 83 a.a.

Genomic Context

ASZ81_RS20960ASZ81_RS20965ASZ81_RS16730ASZ81_RS16735ASZ81_RS16740ASZ81_RS20635ASZ81_RS16750ASZ81_RS16755ASZ81_RS16775ASZ81_RS16780ASZ81_RS16785ASZ81_RS16790ASZ81_RS16795ASZ81_RS16800ASZ81_RS16760ASZ81_RS16765ASZ81_RS16805
Location: 422640..422765 (126 bp)
Type: Others
Protein ID: WP_001944767.1
Location: 422781..422819 (39 bp)
Type: Others
Protein ID: WP_106019119.1
Location: 423032..424036 (1005 bp)
Type: Others
Protein ID: WP_000964925.1
Location: 424189..424635 (447 bp)
Type: Others
Protein ID: WP_000128977.1
Location: 424755..425684 (930 bp)
Type: Others
Protein ID: WP_000335802.1
Location: 425681..425791 (111 bp)
Type: Others
Protein ID: WP_071917832.1
Location: 425819..426295 (477 bp)
Type: Others
Protein ID: WP_001047180.1
Location: 426432..426947 (516 bp)
Type: Others
Protein ID: WP_001201528.1
Location: 428182..428835 (654 bp)
Type: Others
Protein ID: WP_000036957.1
Location: 429107..429532 (426 bp)
Type: Others
Protein ID: WP_000415748.1
Location: 429740..430135 (396 bp)
Type: Others
Protein ID: WP_000649527.1
Location: 430286..430816 (531 bp)
Type: Others
Protein ID: WP_000415563.1
Location: 430954..431454 (501 bp)
Type: Others
Protein ID: WP_000789723.1
Location: 431610..432008 (399 bp)
Type: Others
Protein ID: WP_001882293.1
Location: 427083..427373 (291 bp)
Type: Toxin
Protein ID: WP_000221352.1
Location: 427363..427611 (249 bp)
Type: Antitoxin
Protein ID: WP_000213183.1
Location: 432108..432572 (465 bp)
Type: Others
Protein ID: WP_000140244.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ASZ81_RS20960422640..422765+126WP_001944767.1DUF645 family protein-
ASZ81_RS20965422781..422819+39WP_106019119.1hypothetical protein-
ASZ81_RS16730423032..424036+1005WP_000964925.1LD-carboxypeptidase-
ASZ81_RS16735424189..424635+447WP_000128977.1hypothetical protein-
ASZ81_RS16740424755..425684+930WP_000335802.1hypothetical protein-
ASZ81_RS20635425681..425791+111WP_071917832.1DUF3265 domain-containing protein-
ASZ81_RS16750425819..426295+477WP_001047180.1GNAT family N-acetyltransferase-
ASZ81_RS16755426432..426947+516WP_001201528.1lipocalin family protein-
ASZ81_RS16760427083..427373-291WP_000221352.1type II toxin-antitoxin system RelE/ParE family toxinToxin
ASZ81_RS16765427363..427611-249WP_000213183.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
ASZ81_RS16775428182..428835+654WP_000036957.1site-specific DNA-methyltransferase-
ASZ81_RS16780429107..429532+426WP_000415748.1hypothetical protein-
ASZ81_RS16785429740..430135+396WP_000649527.1DUF3465 domain-containing protein-
ASZ81_RS16790430286..430816+531WP_000415563.1hypothetical protein-
ASZ81_RS16795430954..431454+501WP_000789723.1hypothetical protein-
ASZ81_RS16800431610..432008+399WP_001882293.1hypothetical protein-
ASZ81_RS16805432108..432572-465WP_000140244.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandcatB9-304741..463550158809
insideIntegron--309821..463174153353


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11247.23 Da        Isoelectric Point: 10.4678

>T58271 WP_000221352.1 NZ_CP013306:c427373-427083 [Vibrio cholerae]
MTYKLEFKKSALKEWKKLAVPLQQQFKKKLIERLENPHVPSAKLSGAENIYKIKLRQSGYRLVYQVENDIIVVTVLAVGK
RERSEVYTKALQRLDD

Download         Length: 291 bp

>T58271 NZ_CP013306:c427373-427083 [Vibrio cholerae]
ATGACCTATAAGCTTGAGTTCAAAAAGAGTGCTTTGAAGGAATGGAAAAAGTTAGCCGTTCCACTCCAACAGCAGTTCAA
GAAGAAACTAATAGAACGCCTTGAAAATCCACATGTTCCATCAGCCAAACTGTCTGGCGCTGAGAACATTTATAAAATAA
AACTTCGGCAGTCTGGTTATCGCTTAGTCTATCAAGTTGAAAATGACATCATCGTAGTTACTGTTTTAGCTGTCGGTAAA
CGAGAACGCAGCGAAGTTTACACTAAAGCGCTGCAACGGCTAGACGACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8937.28 Da        Isoelectric Point: 4.1079

>AT58271 WP_000213183.1 NZ_CP013306:c427611-427363 [Vibrio cholerae]
MTTRILADVAASITEFKANPMKVATSAFGAPVAVLNRNEPAFYCVPASTYEIMMDKLEDLELLAIAKERLSEDSVSVNID
DL

Download         Length: 249 bp

>AT58271 NZ_CP013306:c427611-427363 [Vibrio cholerae]
ATGACCACTAGAATCCTAGCTGATGTTGCAGCAAGCATTACCGAATTTAAAGCAAACCCAATGAAAGTTGCAACTAGTGC
CTTCGGTGCTCCTGTTGCTGTACTCAACCGAAATGAGCCGGCTTTCTACTGCGTCCCTGCAAGCACCTACGAGATCATGA
TGGATAAGCTTGAAGATCTTGAGCTACTGGCTATTGCCAAAGAACGCTTAAGTGAAGACAGCGTATCGGTAAATATCGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBH9L4R3

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A366A3W8

References