Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 373190..373730 Replicon chromosome
Accession NZ_OW443148
Organism Vibrio cholerae strain CNRVC190243 isolate YE-NCPHL-19014-PI

Toxin (Protein)


Gene name relE Uniprot ID A0A151JGK8
Locus tag OC617_RS15535 Protein ID WP_000277238.1
Coordinates 373190..373459 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q9KML3
Locus tag OC617_RS15540 Protein ID WP_001258569.1
Coordinates 373452..373730 (-) Length 93 a.a.

Genomic Context

OC617_RS15495OC617_RS15500OC617_RS15505OC617_RS15520OC617_RS15525OC617_RS15530OC617_RS15545OC617_RS15550OC617_RS15555OC617_RS15560OC617_RS15565OC617_RS15570OC617_RS15575OC617_RS15580OC617_RS15585OC617_RS15590OC617_RS15595OC617_RS15600OC617_RS15605OC617_RS15510OC617_RS15515OC617_RS15535OC617_RS15540
Location: 368411..368947 (537 bp)
Type: Others
Protein ID: WP_000469482.1
Location: 369138..369599 (462 bp)
Type: Others
Protein ID: WP_001903091.1
Location: 369664..369732 (69 bp)
Type: Others
Protein ID: Protein_323
Location: 370908..371033 (126 bp)
Type: Others
Protein ID: WP_001900195.1
Location: 371283..371729 (447 bp)
Type: Others
Protein ID: WP_000006157.1
Location: 371792..373003 (1212 bp)
Type: Others
Protein ID: WP_001122813.1
Location: 373781..373898 (118 bp)
Type: Others
Protein ID: Protein_331
Location: 374016..374294 (279 bp)
Type: Others
Protein ID: WP_001921601.1
Location: 374654..374752 (99 bp)
Type: Others
Protein ID: WP_223225486.1
Location: 374952..375053 (102 bp)
Type: Others
Protein ID: WP_001921603.1
Location: 375043..375429 (387 bp)
Type: Others
Protein ID: WP_000703163.1
Location: 375624..375875 (252 bp)
Type: Others
Protein ID: WP_001890111.1
Location: 375848..375997 (150 bp)
Type: Others
Protein ID: WP_071908333.1
Location: 376089..376331 (243 bp)
Type: Others
Protein ID: WP_000107461.1
Location: 376583..376861 (279 bp)
Type: Others
Protein ID: WP_000280324.1
Location: 377293..377336 (44 bp)
Type: Others
Protein ID: Protein_340
Location: 377318..377411 (94 bp)
Type: Others
Protein ID: Protein_341
Location: 377380..377511 (132 bp)
Type: Others
Protein ID: WP_001883067.1
Location: 377683..378150 (468 bp)
Type: Others
Protein ID: WP_001289288.1
Location: 369749..370246 (498 bp)
Type: Others
Protein ID: WP_000982260.1
Location: 370243..370515 (273 bp)
Type: Others
Protein ID: WP_000246253.1
Location: 373190..373459 (270 bp)
Type: Toxin
Protein ID: WP_000277238.1
Location: 373452..373730 (279 bp)
Type: Antitoxin
Protein ID: WP_001258569.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OC617_RS15495 (CNRVC190243H_03086)368411..368947+537WP_000469482.1GNAT family protein-
OC617_RS15500 (CNRVC190243H_03087)369138..369599+462WP_001903091.1lipocalin family protein-
OC617_RS15505369664..369732+69Protein_323acetyltransferase-
OC617_RS15510 (CNRVC190243H_03088)369749..370246-498WP_000982260.1GNAT family N-acetyltransferase-
OC617_RS15515 (CNRVC190243H_03089)370243..370515-273WP_000246253.1DUF1778 domain-containing protein-
OC617_RS15520370908..371033+126WP_001900195.1DUF645 family protein-
OC617_RS15525 (CNRVC190243H_03090)371283..371729+447WP_000006157.1hypothetical protein-
OC617_RS15530 (CNRVC190243H_03091)371792..373003+1212WP_001122813.1IS256 family transposase-
OC617_RS15535 (CNRVC190243H_03092)373190..373459-270WP_000277238.1type II toxin-antitoxin system YafQ family toxinToxin
OC617_RS15540 (CNRVC190243H_03093)373452..373730-279WP_001258569.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
OC617_RS15545373781..373898+118Protein_331DUF3265 domain-containing protein-
OC617_RS15550374016..374294+279WP_001921601.1DUF3709 domain-containing protein-
OC617_RS15555374654..374752+99WP_223225486.1DUF3709 domain-containing protein-
OC617_RS15560374952..375053+102WP_001921603.1hypothetical protein-
OC617_RS15565 (CNRVC190243H_03094)375043..375429+387WP_000703163.1VOC family protein-
OC617_RS15570 (CNRVC190243H_03095)375624..375875+252WP_001890111.1TIGR03643 family protein-
OC617_RS15575375848..375997+150WP_071908333.1DUF3265 domain-containing protein-
OC617_RS15580 (CNRVC190243H_03096)376089..376331+243WP_000107461.1hypothetical protein-
OC617_RS15585376583..376861+279WP_000280324.1DUF3709 domain-containing protein-
OC617_RS15590377293..377336+44Protein_340hypothetical protein-
OC617_RS15595377318..377411+94Protein_341ggdef family protein-
OC617_RS15600377380..377511+132WP_001883067.1hypothetical protein-
OC617_RS15605 (CNRVC190243H_03097)377683..378150+468WP_001289288.1OsmC family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandcatB9-349905..456410106505
insideIntegroncatB9-354985..456034101049
-flankIS/Tn--371792..3730031211


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10406.11 Da        Isoelectric Point: 9.5084

>T295388 WP_000277238.1 NZ_OW443148:c373459-373190 [Vibrio cholerae]
MYKLEYSTQFKKDFKKITKMPISDIIEVGNVISKLQRGEKLEPKNVDHPLTGNWVGFRDCHIKPDLVLIYRVFNDQLQLA
RIGSHSDLF

Download         Length: 270 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10088.58 Da        Isoelectric Point: 6.0728

>AT295388 WP_001258569.1 NZ_OW443148:c373730-373452 [Vibrio cholerae]
MRTEMLSTRIDHDTKIAFTNVCDEMGLSTSQAIKLFAKAVINHGGIPFELRVPQPNEVTASAIQELVEGKGHKAESVEAM
LNELTEGKVKHV

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A151JGK8

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A151KTP9

References