Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 219740..220280 | Replicon | chromosome |
Accession | NZ_LT992493 | ||
Organism | Vibrio cholerae strain 4295STDY6534248 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A151JGK8 |
Locus tag | DG169_RS15460 | Protein ID | WP_000277238.1 |
Coordinates | 219740..220009 (-) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q9KML3 |
Locus tag | DG169_RS15465 | Protein ID | WP_001258569.1 |
Coordinates | 220002..220280 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DG169_RS15390 | 214744..214986 | - | 243 | WP_000557292.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
DG169_RS15395 | 215230..215616 | + | 387 | WP_001015867.1 | NUDIX hydrolase | - |
DG169_RS15400 | 215673..215786 | + | 114 | WP_001900214.1 | hypothetical protein | - |
DG169_RS15405 | 215735..216016 | + | 282 | WP_001894429.1 | DUF1289 domain-containing protein | - |
DG169_RS15420 | 216274..216810 | + | 537 | WP_000469482.1 | GNAT family N-acetyltransferase | - |
DG169_RS15425 | 216947..217462 | + | 516 | WP_001201509.1 | lipocalin family protein | - |
DG169_RS15430 | 217612..218109 | - | 498 | WP_000982260.1 | GNAT family N-acetyltransferase | - |
DG169_RS15435 | 218106..218378 | - | 273 | WP_000246253.1 | DUF1778 domain-containing protein | - |
DG169_RS15440 | 218771..218896 | + | 126 | WP_001900195.1 | DUF645 family protein | - |
DG169_RS15445 | 218912..218950 | + | 39 | WP_106019118.1 | hypothetical protein | - |
DG169_RS15455 | 219146..219592 | + | 447 | WP_000006157.1 | hypothetical protein | - |
DG169_RS15460 | 219740..220009 | - | 270 | WP_000277238.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
DG169_RS15465 | 220002..220280 | - | 279 | WP_001258569.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
DG169_RS15475 | 220566..220844 | + | 279 | WP_001921601.1 | DUF3709 domain-containing protein | - |
DG169_RS15480 | 221096..221302 | + | 207 | Protein_208 | DUF3709 domain-containing protein | - |
DG169_RS15485 | 221502..221603 | + | 102 | WP_001921603.1 | hypothetical protein | - |
DG169_RS15490 | 221593..221979 | + | 387 | WP_000703163.1 | VOC family protein | - |
DG169_RS15495 | 222174..222425 | + | 252 | WP_001890111.1 | TIGR03643 family protein | - |
DG169_RS15500 | 222398..222547 | + | 150 | WP_071908333.1 | DUF3265 domain-containing protein | - |
DG169_RS15505 | 222639..222881 | + | 243 | WP_000107461.1 | hypothetical protein | - |
DG169_RS15510 | 223133..223411 | + | 279 | WP_000280324.1 | DUF3709 domain-containing protein | - |
DG169_RS19815 | 223786..223929 | + | 144 | Protein_215 | DUF645 family protein | - |
DG169_RS19820 | 223983..224021 | + | 39 | WP_082798268.1 | hypothetical protein | - |
DG169_RS15525 | 224233..224700 | + | 468 | WP_001289288.1 | OsmC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | catB9 | - | 197768..293032 | 95264 | |
inside | Integron | catB9 | - | 202848..292656 | 89808 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A151JGK8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A151KTP9 |