Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 388911..389409 Replicon chromosome
Accession NZ_CP046841
Organism Vibrio cholerae strain F9993

Toxin (Protein)


Gene name - Uniprot ID Q9KMK7
Locus tag GPY07_RS16355 Protein ID WP_000589156.1
Coordinates 389143..389409 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID Q9KMK6
Locus tag GPY07_RS16350 Protein ID WP_000643598.1
Coordinates 388911..389156 (-) Length 82 a.a.

Genomic Context

GPY07_RS16305GPY07_RS16315GPY07_RS16320GPY07_RS16325GPY07_RS16330GPY07_RS16335GPY07_RS16340GPY07_RS19455GPY07_RS16345GPY07_RS16350GPY07_RS16355GPY07_RS16360GPY07_RS16365GPY07_RS19460GPY07_RS19465GPY07_RS16375GPY07_RS16380GPY07_RS16385GPY07_RS16390GPY07_RS16395GPY07_RS16400GPY07_RS16405
Location: 384401..384580 (180 bp)
Type: Others
Protein ID: WP_001883058.1
Location: 385158..385268 (111 bp)
Type: Others
Protein ID: WP_079857360.1
Location: 385278..385976 (699 bp)
Type: Others
Protein ID: WP_001890502.1
Location: 386099..386725 (627 bp)
Type: Others
Protein ID: WP_000365424.1
Location: 386767..386859 (93 bp)
Type: Others
Protein ID: WP_014378730.1
Location: 386874..387347 (474 bp)
Type: Others
Protein ID: WP_001161076.1
Location: 387547..387729 (183 bp)
Type: Others
Protein ID: WP_000923182.1
Location: 387790..387918 (129 bp)
Type: Others
Protein ID: WP_071908338.1
Location: 388021..388815 (795 bp)
Type: Others
Protein ID: WP_001911581.1
Location: 388911..389156 (246 bp)
Type: Antitoxin
Protein ID: WP_000643598.1
Location: 389143..389409 (267 bp)
Type: Toxin
Protein ID: WP_000589156.1
Location: 389594..390256 (663 bp)
Type: Others
Protein ID: WP_000960654.1
Location: 390384..390851 (468 bp)
Type: Others
Protein ID: WP_001289288.1
Location: 391063..391101 (39 bp)
Type: Others
Protein ID: WP_082798268.1
Location: 391155..391298 (144 bp)
Type: Others
Protein ID: Protein_400
Location: 391673..391951 (279 bp)
Type: Others
Protein ID: WP_000280324.1
Location: 392203..392445 (243 bp)
Type: Others
Protein ID: WP_000107461.1
Location: 392537..392686 (150 bp)
Type: Others
Protein ID: WP_071908333.1
Location: 392659..392910 (252 bp)
Type: Others
Protein ID: WP_001890111.1
Location: 393105..393491 (387 bp)
Type: Others
Protein ID: WP_000703163.1
Location: 393481..393582 (102 bp)
Type: Others
Protein ID: WP_001921603.1
Location: 393782..393988 (207 bp)
Type: Others
Protein ID: Protein_407
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GPY07_RS16305384401..384580-180WP_001883058.1DUF645 family protein-
GPY07_RS16315385158..385268-111WP_079857360.1DUF3265 domain-containing protein-
GPY07_RS16320385278..385976-699WP_001890502.1hypothetical protein-
GPY07_RS16325386099..386725-627WP_000365424.1LysE family translocator-
GPY07_RS16330386767..386859-93WP_014378730.1DUF3265 domain-containing protein-
GPY07_RS16335386874..387347-474WP_001161076.1GrpB family protein-
GPY07_RS16340387547..387729-183WP_000923182.1DUF645 family protein-
GPY07_RS19455387790..387918-129WP_071908338.1general secretion pathway protein GspI-
GPY07_RS16345388021..388815-795WP_001911581.1hypothetical protein-
GPY07_RS16350388911..389156-246WP_000643598.1hypothetical proteinAntitoxin
GPY07_RS16355389143..389409-267WP_000589156.1BrnT family toxinToxin
GPY07_RS16360389594..390256-663WP_000960654.1hypothetical protein-
GPY07_RS16365390384..390851-468WP_001289288.1OsmC family protein-
GPY07_RS19460391063..391101-39WP_082798268.1hypothetical protein-
GPY07_RS19465391155..391298-144Protein_400DUF645 family protein-
GPY07_RS16375391673..391951-279WP_000280324.1DUF3709 domain-containing protein-
GPY07_RS16380392203..392445-243WP_000107461.1hypothetical protein-
GPY07_RS16385392537..392686-150WP_071908333.1DUF3265 domain-containing protein-
GPY07_RS16390392659..392910-252WP_001890111.1TIGR03643 family protein-
GPY07_RS16395393105..393491-387WP_000703163.1VOC family protein-
GPY07_RS16400393481..393582-102WP_001921603.1hypothetical protein-
GPY07_RS16405393782..393988-207Protein_407DUF3709 domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandcatB9-322056..41902496968
insideIntegron--322432..41223689804


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10092.34 Da        Isoelectric Point: 7.3171

>T145069 WP_000589156.1 NZ_CP046841:c389409-389143 [Vibrio cholerae]
MIKFEFDENKSRSNLEKHGIDFHTAQGLWNDSDLIEIPANTSDEPRYLVVGLLNGKHWSGVITYRGTNIRIISVRRSRKA
EVSLYESA

Download         Length: 267 bp

>T145069 NZ_CP062253:c2324049-2323765 [Pseudomonas gozinkensis]
ATGCAGATTAAGTGGCGACCCAAGGCTCGGGTCGAACTCTCGAAAATACTGAAGTACATTGGCGAGCGAAATTTTGTGGC
GGCGACAGCACTTCACAAGCCAGTCGTAAAAACTACATCTGCGCTTCCTTGGCATCCACACCTGTATCGCAAAGGTCGCT
CTCCCGGCACTCGGGAGATTGTGGTTAGCCCGAACTATCTCGTCGTTTATCAAGTGGCGGACCGAATTGAGATTGTGAGC
ATCTTGCATGCGCGTCAGGAATACCCTCGACGCGACCCCAGTTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9478.77 Da        Isoelectric Point: 6.4832

>AT145069 WP_000643598.1 NZ_CP046841:c389156-388911 [Vibrio cholerae]
MKAHEFDAKFESDDDDIVMDLDLSQAKRPMHKQKRVNVDFPAWMLESLDREASRIGVTRQSIIKIWLAERLESVSHHSSV
R

Download         Length: 246 bp

>AT145069 NZ_CP062253:c2324245-2324039 [Pseudomonas gozinkensis]
ATGATCGACCCGTCTTTGATCGACCCACTGTGCCCGGTTGTTTCGGATCTTGCTCCTGAGGAGCAGGCTGCGAGTTATGA
CCGTTGGTTTCGCGCCGAAGTACAGGCCTCTCTCGATGATCCGCGTCCGAGTATTCCCCATGAGCAAGTGATAGCGGAAA
TAAACGCCTTGATGGAATCAATGCGCAAAAGCGCTGATGCAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A271VMP7

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A271VME2

References