Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00896  |
| T6SS type | Type i3 |
| Strain | Salmonella enterica subsp. enterica serovar Typhimurium |
| Replicon (GenBank) | chromosome (AJ320483) |
| Location | 322..27706 |
| Function | anti-eukaryotic |
| Comment | The SCI island modulates serovar Typhimurium ability to enter eukaryotic cells. |
| References | [1] Folkesson A et al (2002) The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol. 153(8):537-45. [PudMed:12437215] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP010897 | TssA | Locus_01 (sciA) | 322..1377 | - | 1056 | 15130916 | SciA protein |
| T6CP010898 | TssG | Locus_02 (sciB) | 1388..2263 | - | 876 | 15130917 | SciB protein |
| T6CP010899 | TssF | Locus_03 (sciC) | 2382..4265 | - | 1884 | 15130918 | SciC protein |
| T6CP010900 | TssE | Locus_04 (sciD) | 4281..4775 | - | 495 | 15130919 | SciD protein |
| T6CP012908 | TagJ | Locus_05 (sciE) | 4772..5611 | - | 840 | 15130920 | SciE protein |
| Locus_06 (sciF) | 5583..6485 | - | 903 | 15130921 | SciF protein | ||
| T6CP010901 | TssH | Locus_07 (sciG) | 6853..9492 | + | 2640 | 15130922 | SciG protein |
| T6CP010902 | TssB | Locus_08 (sciH) | 9592..10134 | + | 543 | 15130923 | SciH protein |
| T6CP010903 | TssC | Locus_09 (sciI) | 10158..11651 | + | 1494 | 15130924 | SciI protein |
| Locus_10 (sciJ) | 11837..12283 | + | 447 | 15130925 | SciJ protein | ||
| T6CP010904 | TssD | Locus_11 (sciK) | 12537..13022 | + | 486 | 15130926 | SciK protein |
| Locus_12 (sciL) | 13327..13812 | + | 486 | 15130927 | SciL protein | ||
| T6CP010905 | TssD | Locus_13 (sciM) | 14323..14808 | + | 486 | 15130928 | SciM protein |
| T6CP010906 | TssJ | Locus_14 (sciN) | 14920..15411 | + | 492 | 15130929 | SciN protein |
| T6CP010907 | TssK | Locus_15 (sciO) | 15415..16758 | + | 1344 | 15130930 | SciO protein |
| T6CP010908 | TssL | Locus_16 (sciP) | 16755..18059 | + | 1305 | 15130931 | SciP protein |
| Locus_17 (sciQ) | 18064..18837 | + | 774 | 15130932 | SciQ protein | ||
| Locus_18 (sciR) | 19028..19471 | + | 444 | 15130933 | SciR protein | ||
| T6CP010909 | TssM | Locus_19 (sciS) | 19505..23374 | + | 3870 | 15130934 | SciS protein |
| Locus_20 (sciT) | 23374..24162 | + | 789 | 15130935 | SciT protein | ||
| Locus_21 (sciU) | 24159..24575 | + | 417 | 15130936 | SciU protein | ||
| Locus_22 (sciV) | 24599..25120 | + | 522 | 15130937 | SciV protein | ||
| T6CP010910 | TssI | Locus_23 (vrgS) | 25517..27706 | + | 2190 | 15130938 | VrgS protein |
| Locus_24 (sciw) | 27730..28176 | + | 447 | 15130939 | SciW protein | ||
| T6CP012395 | PAAR | Locus_25 (rhs1) | 28195..31791 | + | 3597 | 15130940 | Rhs1 protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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