Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00896 experimental
T6SS type Type i3
Strain Salmonella enterica subsp. enterica serovar Typhimurium
Replicon (GenBank) chromosome (AJ320483)
Location 322..27706
Function anti-eukaryotic
Comment The SCI island modulates serovar Typhimurium ability to enter eukaryotic cells.
References
[1] Folkesson A et al (2002) The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol. 153(8):537-45. [PudMed:12437215]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentPAARTagJTssATssBTssCTssDTssETssFTssGTssHTssITssJTssKTssLTssM
Number111112111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
T6CP010897 TssA Locus_01 (sciA) 322..1377 - 1056 15130916 SciA protein
T6CP010898 TssG Locus_02 (sciB) 1388..2263 - 876 15130917 SciB protein
T6CP010899 TssF Locus_03 (sciC) 2382..4265 - 1884 15130918 SciC protein
T6CP010900 TssE Locus_04 (sciD) 4281..4775 - 495 15130919 SciD protein
T6CP012908 TagJ Locus_05 (sciE) 4772..5611 - 840 15130920 SciE protein
Locus_06 (sciF) 5583..6485 - 903 15130921 SciF protein
T6CP010901 TssH Locus_07 (sciG) 6853..9492 + 2640 15130922 SciG protein
T6CP010902 TssB Locus_08 (sciH) 9592..10134 + 543 15130923 SciH protein
T6CP010903 TssC Locus_09 (sciI) 10158..11651 + 1494 15130924 SciI protein
Locus_10 (sciJ) 11837..12283 + 447 15130925 SciJ protein
T6CP010904 TssD Locus_11 (sciK) 12537..13022 + 486 15130926 SciK protein
Locus_12 (sciL) 13327..13812 + 486 15130927 SciL protein
T6CP010905 TssD Locus_13 (sciM) 14323..14808 + 486 15130928 SciM protein
T6CP010906 TssJ Locus_14 (sciN) 14920..15411 + 492 15130929 SciN protein
T6CP010907 TssK Locus_15 (sciO) 15415..16758 + 1344 15130930 SciO protein
T6CP010908 TssL Locus_16 (sciP) 16755..18059 + 1305 15130931 SciP protein
Locus_17 (sciQ) 18064..18837 + 774 15130932 SciQ protein
Locus_18 (sciR) 19028..19471 + 444 15130933 SciR protein
T6CP010909 TssM Locus_19 (sciS) 19505..23374 + 3870 15130934 SciS protein
Locus_20 (sciT) 23374..24162 + 789 15130935 SciT protein
Locus_21 (sciU) 24159..24575 + 417 15130936 SciU protein
Locus_22 (sciV) 24599..25120 + 522 15130937 SciV protein
T6CP010910 TssI Locus_23 (vrgS) 25517..27706 + 2190 15130938 VrgS protein
Locus_24 (sciw) 27730..28176 + 447 15130939 SciW protein
T6CP012395 PAAR Locus_25 (rhs1) 28195..31791 + 3597 15130940 Rhs1 protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector