Detailed information of component protein


Summary

Component ID T6CP010909
Component protein type TssM
T6SS ID (Type) T6SS00896 experimental (Type i3)
Strain Salmonella enterica subsp. enterica serovar Typhimurium
Replicon chromosome
Sequence Protein sequence (1290 a.a.); Nucleotide sequence (3870 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) -
Coordinate (Strand) 19505..23374 (+)
NCBI ID 15130934
GenBank AJ320483
Uniprot ID Q93IR7_SALTM
KEGG ID seni:CY43_01425
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related_N PF14331.8 3.5e-85 265..538
IcmF-related PF06761.14 1.9e-77 590..915
IcmF_C PF06744.14 6.9e-25 1163..1268
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MQKFLSLLFSRR
Transmembrane helix 13-35 ALAVVGVLVLALLVWFVGPLVSF
Outside 36-39 DTLR
Transmembrane helix 40-62 PLASVGSRVVTIALLLMLLVLWL
Inside 63-68 VNWSMS
Transmembrane helix 69-88 IIGISVLCLAIGFVTPLLAL
Outside 89-97 GDVHPFAPL
Transmembrane helix 98-120 WVRLTLIGFILLMYALYGLYRLW
Inside 121-529 RALRMDEQLLRRFLHPRGEEVPVAGEIKADLRTVNHIVTQAIRQLRQLRVDMPGWRKIFEGKRFLYELPWFMVVGSPGDGKTTALLNTGLQFPLAEQMEQTSRILTVPGGGTLHCDWWFTNEAVLIDTAGRYARHDDGGEASAAQRNAGEWQGFLGLLRKHRPGAPLNGVILTLNVADLTAQSPAERLAACAALRARLAELRETLGIRFPVYLVVTKMDLLPGFSEYFRTLTSHLRAQIWGFTLPYSRRRKAGDPQALHAACAQELARLTLRLDQGLDTRLQEEYDLKSRQRLYTFPREFAALGEPLLEAIEQIFLDSKFDATQLNNTLRGVFFTSAAQAQADAVADQLSIWQRFVRAIKTARGESSASLPHALPDGNRSYFLHDLLTQFIFREAHLVEPNLQWAWRYR
Transmembrane helix 530-547 LLRLGGHLLVLVLAFLLW
Outside 548-1289 QGMQTSQQTNGDYLNEISARATRLDGDVKAYTGKPAMAPVPALLDSARELSAWPELDPDAPPLAWRYGLYSVPPVTDSVASLYNRLLDQLLLPPLVKRMEYVLADAIARQDSKAAYDALRIYLLLNLDKDHEDKYNAAEIQSWVINDLGNSDSVAGFGGRAAVLTHIEALFDGSRVVHSPYEKDEALIRQARAFLDGHTSTERIYARALAAMESEAPQEFTLVRAVGADAGTVFVRSNGAPLDRGVPGIFTREGYRELFDKRLPEFVAAATANDGWVMGRESTPKKLTDSLRSQIPGQEQSVAREVRRLYLTEYARRWQDFLDSIHSINSAGEEGSSGLAYDLQVLRTLASPDSPLMRLGKAVVEQTTLVPPPDPQARQKQLAQRASGNAGKVVQTAKLFQDIHPEERLEKTLVDDRFAALREVIAGRTDGGQSGGGTMQIASLLTMLNEYYTQLTIADSALAAGTLPARITAADKLQLEAAKLPAPLKNILLDLTKQGTRKINAGTGDVLNTQMEAMMGDDCRDAIDGRYPFADSPQEVSAEDFNRIFASGGVLDAFWSKQLAPLADTASDPWRYKPTEGNMTLQGPDLTPFQQAKQIRSVFFNSEGGKKFSWSMQISVVDMDPAITELVIDIDGQVLRYAHGPDRPLKVTWPGPRNGSMAEITASPRIRQDTSTLLTGGPWALFHLLDAGMVQETAVRGRQLVEYDFDGRRVVLEITAGRDFNPVSRELLQNFSCPARAL


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9933 - -


  Protein sequence: 1290 a.a.    

>T6CP010909 AJ320483:19505-23374 [Salmonella enterica subsp. enterica serovar Typhimurium] [TssM]
MQKFLSLLFSRRALAVVGVLVLALLVWFVGPLVSFDTLRPLASVGSRVVTIALLLMLLVLWLVNWSMSIIGISVLCLAIG
FVTPLLALGDVHPFAPLWVRLTLIGFILLMYALYGLYRLWRALRMDEQLLRRFLHPRGEEVPVAGEIKADLRTVNHIVTQ
AIRQLRQLRVDMPGWRKIFEGKRFLYELPWFMVVGSPGDGKTTALLNTGLQFPLAEQMEQTSRILTVPGGGTLHCDWWFT
NEAVLIDTAGRYARHDDGGEASAAQRNAGEWQGFLGLLRKHRPGAPLNGVILTLNVADLTAQSPAERLAACAALRARLAE
LRETLGIRFPVYLVVTKMDLLPGFSEYFRTLTSHLRAQIWGFTLPYSRRRKAGDPQALHAACAQELARLTLRLDQGLDTR
LQEEYDLKSRQRLYTFPREFAALGEPLLEAIEQIFLDSKFDATQLNNTLRGVFFTSAAQAQADAVADQLSIWQRFVRAIK
TARGESSASLPHALPDGNRSYFLHDLLTQFIFREAHLVEPNLQWAWRYRLLRLGGHLLVLVLAFLLWQGMQTSQQTNGDY
LNEISARATRLDGDVKAYTGKPAMAPVPALLDSARELSAWPELDPDAPPLAWRYGLYSVPPVTDSVASLYNRLLDQLLLP
PLVKRMEYVLADAIARQDSKAAYDALRIYLLLNLDKDHEDKYNAAEIQSWVINDLGNSDSVAGFGGRAAVLTHIEALFDG
SRVVHSPYEKDEALIRQARAFLDGHTSTERIYARALAAMESEAPQEFTLVRAVGADAGTVFVRSNGAPLDRGVPGIFTRE
GYRELFDKRLPEFVAAATANDGWVMGRESTPKKLTDSLRSQIPGQEQSVAREVRRLYLTEYARRWQDFLDSIHSINSAGE
EGSSGLAYDLQVLRTLASPDSPLMRLGKAVVEQTTLVPPPDPQARQKQLAQRASGNAGKVVQTAKLFQDIHPEERLEKTL
VDDRFAALREVIAGRTDGGQSGGGTMQIASLLTMLNEYYTQLTIADSALAAGTLPARITAADKLQLEAAKLPAPLKNILL
DLTKQGTRKINAGTGDVLNTQMEAMMGDDCRDAIDGRYPFADSPQEVSAEDFNRIFASGGVLDAFWSKQLAPLADTASDP
WRYKPTEGNMTLQGPDLTPFQQAKQIRSVFFNSEGGKKFSWSMQISVVDMDPAITELVIDIDGQVLRYAHGPDRPLKVTW
PGPRNGSMAEITASPRIRQDTSTLLTGGPWALFHLLDAGMVQETAVRGRQLVEYDFDGRRVVLEITAGRDFNPVSRELLQ
NFSCPARAL*

  Nucleotide sequence: 3870 bp    

>T6CP010909 AJ320483:19505-23374 [Salmonella enterica subsp. enterica serovar Typhimurium] [TssM]
ATGCAAAAATTTCTTAGTCTGCTTTTTTCCCGGCGCGCGCTGGCAGTTGTGGGCGTTCTGGTTCTGGCGCTGCTGGTCTG
GTTTGTCGGGCCGCTGGTGTCATTTGATACCCTGCGCCCGCTGGCCTCCGTGGGTAGCCGGGTAGTGACCATTGCCCTGT
TGCTGATGCTGCTGGTACTGTGGCTGGTCAACTGGTCGATGAGTATCATCGGCATCAGTGTCCTGTGCCTGGCGATTGGC
TTCGTCACACCGCTGCTGGCCCTGGGCGATGTCCATCCGTTTGCGCCGCTGTGGGTCCGCCTGACCCTGATTGGTTTCAT
CCTGCTGATGTACGCGCTGTACGGCCTGTACCGGCTGTGGCGTGCGCTGCGTATGGATGAACAACTGCTGCGTCGCTTCC
TGCATCCGCGCGGGGAAGAGGTACCGGTGGCAGGCGAGATCAAAGCCGACCTGCGCACCGTCAACCATATTGTCACGCAG
GCCATCCGGCAGCTGCGGCAGTTGCGGGTGGATATGCCTGGCTGGCGTAAAATCTTCGAGGGAAAACGCTTTCTGTATGA
GCTGCCGTGGTTCATGGTGGTCGGCAGTCCCGGCGACGGCAAAACCACGGCCCTGCTGAACACCGGATTGCAGTTCCCGC
TGGCGGAGCAAATGGAGCAGACTTCGCGCATCCTGACAGTACCGGGTGGCGGCACGCTACACTGCGACTGGTGGTTTACC
AACGAAGCGGTGTTGATTGATACCGCCGGACGCTACGCCCGCCACGATGACGGTGGTGAAGCGAGCGCCGCGCAGCGTAA
CGCCGGAGAGTGGCAGGGCTTTCTCGGTCTGCTGCGTAAACATCGCCCCGGCGCGCCGCTTAACGGCGTGATCCTGACGC
TAAACGTGGCGGATTTAACCGCACAGTCACCGGCGGAACGCCTGGCGGCCTGCGCCGCTCTGCGGGCGCGACTGGCAGAA
CTGCGCGAGACCCTGGGGATTCGCTTTCCGGTCTATCTGGTGGTCACCAAAATGGATTTGTTGCCGGGGTTCAGCGAATA
TTTTCGCACGCTGACCAGCCATCTTCGTGCACAAATCTGGGGCTTCACGTTGCCGTACAGCCGCAGGCGAAAAGCGGGCG
ACCCGCAGGCGCTGCACGCCGCCTGCGCGCAGGAGCTGGCGCGCCTGACGCTGCGGTTGGATCAGGGACTGGATACCCGG
TTACAGGAAGAGTACGACCTTAAAAGCCGCCAGCGGCTGTATACCTTCCCGCGTGAGTTCGCCGCCCTCGGCGAGCCGTT
GCTGGAGGCTATTGAACAGATCTTCCTCGATTCAAAATTCGATGCCACGCAACTGAATAACACGCTGCGCGGGGTGTTTT
TCACCAGCGCCGCGCAGGCGCAGGCCGACGCCGTGGCCGACCAGTTGAGTATCTGGCAGCGCTTTGTCCGGGCGATAAAA
ACCGCCCGTGGCGAATCCTCCGCCTCTCTCCCACACGCTCTGCCGGACGGCAACCGCAGCTACTTCCTGCATGACCTGCT
GACACAGTTTATTTTTCGTGAAGCGCACCTGGTGGAGCCAAACCTCCAGTGGGCCTGGCGTTACCGCCTGCTGCGCCTCG
GCGGGCACCTGCTGGTACTGGTGCTGGCATTCCTGTTGTGGCAGGGGATGCAGACCAGCCAGCAGACCAACGGCGACTAT
CTGAATGAAATCAGCGCCCGCGCGACCCGGCTGGACGGTGATGTGAAAGCCTACACCGGTAAACCGGCGATGGCTCCCGT
CCCGGCACTGCTGGACAGCGCAAGGGAACTGTCCGCCTGGCCGGAACTGGACCCGGACGCGCCGCCGCTGGCCTGGCGCT
ACGGTCTGTACAGCGTACCGCCGGTAACCGACAGCGTGGCGTCGCTGTACAACCGTCTGCTGGATCAACTGCTGCTGCCG
CCGCTGGTGAAACGGATGGAGTATGTGCTGGCGGACGCCATTGCCCGTCAGGATAGTAAAGCGGCCTACGATGCCCTGCG
CATCTATCTGCTACTGAATCTGGATAAAGATCACGAAGATAAATACAACGCGGCGGAGATCCAGTCGTGGGTGATTAACG
ATCTGGGGAACAGCGACAGCGTGGCCGGGTTCGGCGGGCGCGCCGCCGTGCTGACGCATATCGAAGCGCTGTTTGACGGC
AGCCGGGTGGTGCATTCACCGTATGAGAAAGATGAGGCGCTGATCCGCCAGGCGCGGGCATTCCTCGACGGTCACACCAG
TACCGAGCGTATCTACGCGCGGGCGCTGGCGGCAATGGAGAGCGAAGCGCCGCAGGAGTTCACGCTGGTACGCGCCGTCG
GCGCGGATGCGGGAACGGTCTTTGTGCGTAGCAACGGCGCGCCGCTGGATCGGGGCGTGCCGGGTATTTTTACCCGTGAA
GGATACCGGGAGCTGTTCGACAAACGATTACCGGAATTTGTGGCGGCGGCGACGGCGAACGATGGCTGGGTGATGGGCCG
GGAGAGTACGCCAAAAAAGCTGACTGACAGCCTGCGCAGCCAGATACCGGGGCAGGAGCAGTCTGTCGCCCGCGAAGTCC
GCCGTTTGTACCTGACGGAATATGCCCGCCGCTGGCAGGATTTTCTGGACAGTATCCATAGTATCAACAGTGCCGGGGAA
GAGGGCAGTTCCGGCCTGGCCTATGATTTACAGGTGCTGCGCACCCTGGCGTCGCCGGACTCACCGCTGATGCGGCTGGG
AAAAGCGGTGGTGGAGCAGACCACGCTGGTGCCGCCGCCGGACCCGCAGGCCAGACAGAAACAACTGGCGCAGCGCGCAT
CCGGTAACGCGGGGAAAGTGGTACAGACGGCAAAACTGTTCCAGGATATTCACCCGGAAGAACGGCTGGAAAAAACGCTG
GTGGATGATCGTTTCGCCGCGCTGCGCGAGGTCATTGCCGGGCGGACGGACGGCGGACAGAGCGGCGGTGGGACGATGCA
GATCGCTTCGCTGCTGACCATGCTCAACGAGTATTACACCCAACTGACCATTGCTGATAGCGCGCTGGCGGCGGGGACGT
TGCCAGCGCGCATTACTGCCGCAGACAAGTTGCAACTGGAGGCGGCGAAACTGCCCGCGCCGCTGAAAAACATCCTGCTG
GATCTGACGAAGCAGGGAACGCGCAAAATCAACGCCGGGACCGGCGACGTGCTGAACACCCAGATGGAGGCGATGATGGG
CGACGACTGCCGTGACGCCATCGACGGGCGCTATCCGTTCGCCGACAGTCCGCAGGAGGTCAGCGCCGAGGACTTTAACC
GCATCTTCGCCAGCGGCGGCGTACTGGATGCTTTCTGGAGCAAACAACTGGCTCCGCTGGCGGACACCGCCAGCGACCCG
TGGCGCTACAAACCGACCGAAGGCAACATGACATTGCAGGGGCCGGATCTGACGCCGTTTCAGCAGGCGAAGCAGATCCG
CAGCGTATTTTTTAACAGCGAGGGCGGGAAAAAATTTTCCTGGTCGATGCAGATTAGCGTGGTGGATATGGACCCGGCCA
TCACGGAACTGGTGATTGATATCGACGGCCAGGTGCTGCGCTACGCCCATGGTCCGGACCGTCCCCTGAAAGTAACGTGG
CCGGGACCGCGCAACGGCTCGATGGCGGAAATCACCGCCAGCCCGCGTATTCGCCAGGACACCTCAACGCTACTGACCGG
CGGGCCGTGGGCGCTGTTTCATCTGCTGGACGCCGGAATGGTACAGGAAACGGCGGTGCGGGGGCGTCAACTGGTGGAAT
ATGATTTTGACGGTCGCCGGGTGGTGCTGGAAATCACCGCCGGGCGGGATTTTAACCCGGTCAGCCGGGAGCTGTTGCAG
AACTTCAGTTGCCCGGCGAGGGCGCTGTAA