Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00049  |
| T6SS type | Type i4b |
| Strain | Chromobacterium violaceum ATCC 12472 |
| Replicon (RefSeq) | chromosome (NC_005085) |
| Location | 4278258..4321021 |
| Function | - |
| Comment | - |
| References | [1] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] [2] Stauff DL, Bassler BL. et al (2011) Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.. J Bacteriol. 193(15):3871-8. [PudMed:21622734] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| CV_RS22390 | 4273307..4274488 | - | 1182 | WP_011137500.1 | SDR family oxidoreductase | ||
| CV_RS19590 | 4274545..4275618 | - | 1074 | WP_080509138.1 | polyprenyl synthetase family protein | ||
| CV_RS19595 | 4275660..4276589 | - | 930 | WP_011137502.1 | hypothetical protein | ||
| CV_RS19600 | 4276591..4277475 | - | 885 | WP_011137503.1 | UbiA family prenyltransferase | ||
| CV_RS19605 | 4277480..4278247 | - | 768 | WP_011137504.1 | HAD hydrolase-like protein | ||
| CV_RS19610 | 4278258..4279427 | - | 1170 | WP_158303334.1 | polyprenyl synthetase family protein | ||
| CV_RS19615 (asnB) | 4279442..4281430 | - | 1989 | WP_011137506.1 | asparagine synthase (glutamine-hydrolyzing) | ||
| CV_RS19620 | 4281435..4282250 | - | 816 | WP_011137507.1 | isopentenyl phosphate kinase family protein | ||
| CV_RS19625 | 4282261..4282986 | - | 726 | WP_011137508.1 | (5-formylfuran-3-yl)methyl phosphate synthase | ||
| T6CP000412 | TssA | CV_RS19630 (tssA) | 4283686..4284771 | - | 1086 | WP_011137510.1 | type VI secretion system protein TssA |
| CV_RS19635 | 4284781..4285044 | - | 264 | WP_043596788.1 | PAAR domain-containing protein | ||
| CV_RS19640 | 4285041..4286477 | - | 1437 | WP_043596790.1 | hypothetical protein | ||
| T6CP000413 | TssH | CV_RS19645 (tssH) | 4286490..4289129 | - | 2640 | WP_043596793.1 | type VI secretion system ATPase TssH |
| CV_RS19650 | 4289166..4289873 | - | 708 | WP_043596794.1 | hypothetical protein | ||
| T6CP000414 | TssG | CV_RS19655 (tssG) | 4289891..4290928 | - | 1038 | WP_043598348.1 | type VI secretion system baseplate subunit TssG |
| CV_RS19660 | 4290915..4291214 | - | 300 | WP_011137515.1 | hypothetical protein | ||
| T6CP000415 | TssF | CV_RS19665 (tssF) | 4291222..4293081 | - | 1860 | WP_011137516.1 | type VI secretion system baseplate subunit TssF |
| CV_RS22395 | 4293147..4293779 | - | 633 | WP_147296213.1 | hypothetical protein | ||
| CV_RS19675 | 4293888..4295963 | - | 2076 | WP_011137518.1 | DUF2235 domain-containing protein | ||
| CV_RS22400 | 4295951..4296499 | - | 549 | WP_011137519.1 | DUF3304 domain-containing protein | ||
| CV_RS22405 | 4296545..4297087 | - | 543 | WP_011137520.1 | DUF3304 domain-containing protein | ||
| CV_RS22410 | 4297084..4297875 | - | 792 | WP_052278879.1 | DUF4123 domain-containing protein | ||
| CV_RS19695 | 4297962..4300490 | - | 2529 | pseudogene | type VI secretion system tip protein VgrG | ||
| T6CP011439 | TagL | CV_RS19700 | 4300599..4301036 | - | 438 | WP_011137523.1 | OmpA family protein |
| T6CP000417 | TssD | CV_RS19705 | 4301111..4301608 | - | 498 | WP_011137524.1 | type VI secretion system tube protein Hcp |
| T6CP000418 | TssC | CV_RS19710 (tssC) | 4301678..4303156 | - | 1479 | WP_011137525.1 | type VI secretion system contractile sheath large subunit |
| T6CP000419 | TssB | CV_RS19715 (tssB) | 4303153..4303659 | - | 507 | WP_011137526.1 | type VI secretion system contractile sheath small subunit |
| CV_RS19720 (tagF) | 4303701..4304717 | - | 1017 | WP_043598356.1 | type VI secretion system-associated protein TagF | ||
| T6CP000420 | TssM | CV_RS19725 (tssM) | 4304734..4308516 | - | 3783 | WP_011137527.1 | type VI secretion system membrane subunit TssM |
| CV_RS19730 | 4308545..4309402 | - | 858 | WP_011137528.1 | M15 family metallopeptidase | ||
| T6CP000421 | TssJ | CV_RS23100 (tssJ) | 4309602..4310102 | + | 501 | WP_158303335.1 | type VI secretion system lipoprotein TssJ |
| T6CP000422 | TssK | CV_RS19740 (tssK) | 4310149..4311495 | + | 1347 | WP_011137530.1 | type VI secretion system baseplate subunit TssK |
| T6CP000423 | TssL | CV_RS19745 | 4311503..4312204 | + | 702 | WP_011137531.1 | type IVB secretion system protein IcmH/DotU |
| T6CP000424 | TssE | CV_RS19750 (tssE) | 4312201..4312680 | + | 480 | WP_011137532.1 | type VI secretion system baseplate subunit TssE |
| T6CP000425 | TssI | CV_RS19755 | 4312701..4315319 | + | 2619 | WP_011137533.1 | type VI secretion system tip protein VgrG |
| CV_RS19760 | 4315330..4316205 | + | 876 | WP_011137534.1 | DUF4123 domain-containing protein | ||
| CV_RS23105 | 4316633..4317145 | + | 513 | WP_011137536.1 | DUF3304 domain-containing protein | ||
| CV_RS19775 | 4317142..4318794 | + | 1653 | WP_115610271.1 | DUF2235 domain-containing protein | ||
| CV_RS19780 | 4318787..4320046 | + | 1260 | WP_147296214.1 | hypothetical protein | ||
| CV_RS19785 (cyoE) | 4320113..4321021 | - | 909 | WP_011137539.1 | heme o synthase | ||
| CV_RS19790 (cyoD) | 4321033..4321353 | - | 321 | WP_011137540.1 | cytochrome o ubiquinol oxidase subunit IV | ||
| CV_RS19795 (cyoC) | 4321353..4321964 | - | 612 | WP_011137541.1 | cytochrome o ubiquinol oxidase subunit III | ||
| CV_RS19800 (cyoB) | 4321980..4324022 | - | 2043 | WP_011137542.1 | cytochrome o ubiquinol oxidase subunit I | ||
| CV_RS19805 (cyoA) | 4324029..4324970 | - | 942 | WP_011137543.1 | ubiquinol oxidase subunit II |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0120 |
CV_RS20220 (CviR) | protein | QS regulatory pathway | Chromobacterium violaceum ATCC 12472 | chromosome (NC_005085) | 4426186..4427046 (+) | 1169634970 | CV_RS06990 (VgrG) promotor (↓) |
| REG0121 |
CV_RS23145 (CviI) | protein | QS regulatory pathway | Chromobacterium violaceum ATCC 12472 | chromosome (NC_005085) | 4426967..4427620 (-) | 499450174 | CV_RS20220 (CviR) (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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