Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R8586_RS10625 Genome accession   NZ_AP026922
Coordinates   2009581..2009772 (-) Length   63 a.a.
NCBI ID   WP_025169467.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2004581..2014772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS10590 (PC0038_20660) - 2004639..2005514 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R8586_RS10595 (PC0038_20670) pstC 2005632..2006495 (+) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  R8586_RS10600 (PC0038_20680) pstA 2006488..2007303 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R8586_RS10605 (PC0038_20690) pstB 2007305..2008057 (+) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  R8586_RS10610 (PC0038_20700) phoU 2008072..2008722 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  R8586_RS10615 (PC0038_20710) - 2008763..2009215 (+) 453 Protein_2049 transposase -
  R8586_RS10620 (PC0038_20720) - 2009330..2009581 (-) 252 WP_001818970.1 hypothetical protein -
  R8586_RS10625 (PC0038_20730) comR 2009581..2009772 (-) 192 WP_025169467.1 helix-turn-helix domain-containing protein Regulator
  R8586_RS10630 (PC0038_20740) - 2009984..2011000 (+) 1017 WP_000415116.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R8586_RS10635 (PC0038_20750) galU 2011022..2011921 (+) 900 WP_000202235.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R8586_RS10640 (PC0038_20760) - 2011993..2012670 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R8586_RS10645 (PC0038_20770) - 2012654..2013193 (-) 540 WP_000834303.1 5-formyltetrahydrofolate cyclo-ligase -
  R8586_RS10650 (PC0038_20780) - 2013205..2014335 (-) 1131 WP_000885071.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 63 a.a.        Molecular weight: 7280.52 Da        Isoelectric Point: 10.6965

>NTDB_id=98148 R8586_RS10625 WP_025169467.1 2009581..2009772(-) (comR) [Streptococcus pneumoniae strain PZ900700038]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGGVKITS

Nucleotide


Download         Length: 192 bp        

>NTDB_id=98148 R8586_RS10625 WP_025169467.1 2009581..2009772(-) (comR) [Streptococcus pneumoniae strain PZ900700038]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGGGGTGAAGATTACAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

57.895

90.476

0.524
  comR Streptococcus pyogenes MGAS8232

57.895

90.476

0.524
  comR Streptococcus mutans UA159

57.895

90.476

0.524
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

60

87.302

0.524
  comR Streptococcus salivarius strain HSISS4

56.604

84.127

0.476
  comR Streptococcus salivarius SK126

56.604

84.127

0.476
  comR Streptococcus suis D9

53.571

88.889

0.476
  comR Streptococcus suis 05ZYH33

53.571

88.889

0.476
  comR Streptococcus suis P1/7

53.571

88.889

0.476
  comR Streptococcus thermophilus LMD-9

54.717

84.127

0.46
  comR Streptococcus thermophilus LMG 18311

54.717

84.127

0.46
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

50

92.063

0.46
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

61.702

74.603

0.46

Multiple sequence alignment