Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R8586_RS10340 Genome accession   NZ_AP026922
Coordinates   1962705..1963007 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1957705..1968007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS10315 (PC0038_20260) comYH 1958510..1959463 (-) 954 WP_000345118.1 class I SAM-dependent methyltransferase Machinery gene
  R8586_RS10320 - 1959809..1960610 (+) 802 WP_128887635.1 IS5 family transposase -
  R8586_RS10325 (PC0038_20290) - 1960761..1961237 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  R8586_RS10330 (PC0038_20300) comGG/cglG 1961911..1962303 (-) 393 WP_001818966.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8586_RS10335 (PC0038_20310) comGF/cglF 1962281..1962742 (-) 462 WP_000250537.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8586_RS10340 (PC0038_20320) comGE/cglE 1962705..1963007 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8586_RS10345 (PC0038_20330) comGD/cglD 1962970..1963374 (-) 405 WP_000588017.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8586_RS10350 (PC0038_20340) comGC/cglC 1963367..1963693 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  R8586_RS10355 (PC0038_20350) comGB/cglB 1963695..1964711 (-) 1017 WP_001844019.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8586_RS10360 (PC0038_20360) comGA/cglA/cilD 1964659..1965600 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8586_RS10365 (PC0038_20370) - 1965676..1966041 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8586_RS10370 (PC0038_20380) - 1966192..1967250 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=98142 R8586_RS10340 WP_000413382.1 1962705..1963007(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700038]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=98142 R8586_RS10340 WP_000413382.1 1962705..1963007(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700038]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment