Detailed information NTG0098144

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R8586_RS10350
• Genome accession: NZ_AP026922
• Coordinates: 1963367..1963693 (-)
• Length: 108 a.a.
• NCBI ID: WP_000738625.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700038
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1958367..1968693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8586_RS10315 (PC0038_20260)	comYH	1958510..1959463 (-)	954	WP_000345118.1	class I SAM-dependent methyltransferase	Machinery gene
R8586_RS10320	-	1959809..1960610 (+)	802	WP_128887635.1	IS5 family transposase	-
R8586_RS10325 (PC0038_20290)	-	1960761..1961237 (+)	477	WP_000777686.1	GNAT family N-acetyltransferase	-
R8586_RS10330 (PC0038_20300)	comGG/cglG	1961911..1962303 (-)	393	WP_001818966.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8586_RS10335 (PC0038_20310)	comGF/cglF	1962281..1962742 (-)	462	WP_000250537.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8586_RS10340 (PC0038_20320)	comGE/cglE	1962705..1963007 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8586_RS10345 (PC0038_20330)	comGD/cglD	1962970..1963374 (-)	405	WP_000588017.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8586_RS10350 (PC0038_20340)	comGC/cglC	1963367..1963693 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
R8586_RS10355 (PC0038_20350)	comGB/cglB	1963695..1964711 (-)	1017	WP_001844019.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8586_RS10360 (PC0038_20360)	comGA/cglA/cilD	1964659..1965600 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R8586_RS10365 (PC0038_20370)	-	1965676..1966041 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8586_RS10370 (PC0038_20380)	-	1966192..1967250 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
R8586_RS10375 (PC0038_20390)	nagA	1967413..1968564 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12143.28 Da
• Isoelectric Point: 10.0055

>NTDB_id=98144 R8586_RS10350 WP_000738625.1 1963367..1963693(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700038]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=98144 R8586_RS10350 WP_000738625.1 1963367..1963693(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700038]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae Rx1	92.593	100	0.926
comGC/cglC	Streptococcus pneumoniae D39	92.593	100	0.926
comGC/cglC	Streptococcus pneumoniae R6	92.593	100	0.926
comGC/cglC	Streptococcus pneumoniae TIGR4	92.593	100	0.926
comGC/cglC	Streptococcus mitis NCTC 12261	92.857	90.741	0.843
comYC	Streptococcus gordonii str. Challis substr. CH1	67.961	95.37	0.648
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comGC	Lactococcus lactis subsp. cremoris KW2	56.863	94.444	0.537
comYC	Streptococcus suis isolate S10	64.773	81.481	0.528
comGC	Staphylococcus aureus MW2	47.674	79.63	0.38
comGC	Staphylococcus aureus N315	47.674	79.63	0.38