Detailed information NTG0972994

Bioinformatically predicted

Overview

• Name: comX
• Type: Regulator
• Locus tag: AAAF57_RS09450
• Genome accession: NZ_CP150847
• Coordinates: 2046530..2047027 (-)
• Length: 165 a.a.
• NCBI ID: WP_002885610.1
• Uniprot ID: A0A2I1TJX9
• Organism: Streptococcus salivarius strain KSS5
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2047763..2048053	2046530..2047027	flank	736

Gene organization within MGE regions

Location: 2046530..2048053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAAF57_RS09450 (AAAF57_09495)	comX	2046530..2047027 (-)	498	WP_002885610.1	sigma factor	Regulator
AAAF57_RS09455 (AAAF57_09500)	tnpA	2047580..2048053 (-)	474	Protein_1843	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20008.84 Da
• Isoelectric Point: 4.9953

>NTDB_id=972994 AAAF57_RS09450 WP_002885610.1 2046530..2047027(-) (comX) [Streptococcus salivarius strain KSS5]
MEQEVFVHAYEVVRPIVLKASRQYFIQLWDLADMEQEAMMTLYQLLEKFPELKSDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYIEISDIAFCLPNKELDAVDRLVYDEQLNAFRNQLSSEDATKLDRLLAGECFRGRKKMIRELKFWMVDFDP
YNEDD

Nucleotide

• Length: 498 bp

>NTDB_id=972994 AAAF57_RS09450 WP_002885610.1 2046530..2047027(-) (comX) [Streptococcus salivarius strain KSS5]
ATGGAACAAGAAGTTTTTGTTCATGCATATGAAGTTGTAAGGCCGATTGTACTTAAGGCTAGTAGACAATATTTCATCCA
ACTTTGGGACCTTGCTGATATGGAGCAAGAGGCTATGATGACGCTTTATCAGCTTTTAGAAAAGTTTCCTGAATTAAAGT
CTGATGATGATAAGTTACGGCGTTATTTTAAAACTAAATTTAGGAATAGACTTAATGATGAGGTTAGAAGGCAGGAGTCT
GTAAAACGTCAAGCTAATCGACAATGTTATATTGAAATTTCAGATATTGCTTTTTGTCTTCCAAATAAAGAGTTAGATGC
TGTTGATAGGCTTGTTTATGATGAGCAGCTTAATGCTTTCCGTAATCAGTTGTCTTCGGAAGATGCTACTAAGTTAGACC
GTTTGCTAGCTGGGGAGTGTTTTAGAGGTCGAAAAAAGATGATCAGAGAGTTAAAATTTTGGATGGTTGATTTTGATCCT
TACAATGAAGATGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2I1TJX9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX	Streptococcus salivarius SK126	100	100	1
comX/sigX	Streptococcus salivarius strain HSISS4	99.394	100	0.994
comX	Streptococcus thermophilus LMD-9	88.485	100	0.885
comX	Streptococcus thermophilus LMG 18311	88.485	100	0.885
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comX	Streptococcus sobrinus strain NIDR 6715-7	40.606	100	0.406
comX/sigX	Streptococcus mutans UA159	41.667	94.545	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.026	94.545	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37