Detailed information NTG0964580

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: NYE79_RS01045
• Genome accession: NZ_CP150168
• Coordinates: 183533..183856 (+)
• Length: 107 a.a.
• NCBI ID: WP_000735800.1
• Uniprot ID: A0A0F2DUU0
• Organism: Streptococcus sp. FSL W8-0197
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 178533..188856

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NYE79_RS01025 (NYE79_01025)	nagA	179890..181041 (+)	1152	WP_216728918.1	N-acetylglucosamine-6-phosphate deacetylase	-
NYE79_RS01030 (NYE79_01030)	-	181196..181561 (+)	366	WP_216728919.1	DUF1033 family protein	-
NYE79_RS01035 (NYE79_01035)	comGA/cglA/cilD	181626..182567 (+)	942	WP_216728920.1	competence type IV pilus ATPase ComGA	Machinery gene
NYE79_RS01040 (NYE79_01040)	comGB/cglB	182515..183531 (+)	1017	WP_216728921.1	competence type IV pilus assembly protein ComGB	Machinery gene
NYE79_RS01045 (NYE79_01045)	comGC/cglC	183533..183856 (+)	324	WP_000735800.1	competence type IV pilus major pilin ComGC	Machinery gene
NYE79_RS01050 (NYE79_01050)	comGD/cglD	183819..184253 (+)	435	WP_216728922.1	competence type IV pilus minor pilin ComGD	Machinery gene
NYE79_RS01055 (NYE79_01055)	comGE/cglE	184216..184518 (+)	303	WP_200370534.1	competence type IV pilus minor pilin ComGE	Machinery gene
NYE79_RS01060 (NYE79_01060)	comGF/cglF	184481..184942 (+)	462	WP_070568120.1	competence type IV pilus minor pilin ComGF	Machinery gene
NYE79_RS01065 (NYE79_01065)	comGG/cglG	184920..185333 (+)	414	WP_070568123.1	competence type IV pilus minor pilin ComGG	Machinery gene
NYE79_RS01070 (NYE79_01070)	-	185366..185956 (+)	591	WP_216728923.1	class I SAM-dependent methyltransferase	-
NYE79_RS01075 (NYE79_01075)	comYH	186015..186968 (+)	954	WP_216728924.1	class I SAM-dependent methyltransferase	Machinery gene
NYE79_RS01080 (NYE79_01080)	-	187019..188209 (+)	1191	WP_000167790.1	acetate kinase	-
NYE79_RS01085 (NYE79_01085)	rnpA	188359..188730 (+)	372	WP_000748120.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11835.95 Da
• Isoelectric Point: 10.0527

>NTDB_id=964580 NYE79_RS01045 WP_000735800.1 183533..183856(+) (comGC/cglC) [Streptococcus sp. FSL W8-0197]
MKKLMTNLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=964580 NYE79_RS01045 WP_000735800.1 183533..183856(+) (comGC/cglC) [Streptococcus sp. FSL W8-0197]
ATGAAAAAACTCATGACAAATTTAAAAAAAGCCAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTTTTGCTTAT
CATCAGCGTTCTTCTCTTGCTCTTTGTTCCTAATTTGACCAAGCAAAAGGATGCCGTCGATGACAAAGGAAAAGCTGCTG
TTGTCAAGGTCGTAGAAAGCCAGGCAGAGCTCTATAGTCTGGACAAGAATGAAGATGCTAGCCTAAGCAAATTACAAGCA
GACGGTCGTATCACAGCTGAGCAAGCTAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A0F2DUU0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	93.458	100	0.935
comGC/cglC	Streptococcus mitis SK321	90.909	92.523	0.841
comGC/cglC	Streptococcus pneumoniae R6	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae Rx1	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae D39	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae TIGR4	87.879	92.523	0.813
comYC	Streptococcus gordonii str. Challis substr. CH1	67.619	98.131	0.664
comYC	Streptococcus mutans UA140	69.072	90.654	0.626
comYC	Streptococcus mutans UA159	69.072	90.654	0.626
comYC	Streptococcus suis isolate S10	67.045	82.243	0.551
comGC	Lactococcus lactis subsp. cremoris KW2	56.436	94.393	0.533