Detailed information NTG0940811

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: V6U69_RS09465
• Genome accession: NZ_CP145867
• Coordinates: 2047288..2047785 (-)
• Length: 165 a.a.
• NCBI ID: WP_060973245.1
• Uniprot ID: A0A2W1I7B4
• Organism: Streptococcus salivarius strain KSS10
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2042288..2052785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U69_RS09445 (V6U69_09435)	-	2042313..2043917 (-)	1605	WP_073685756.1	CTP synthase	-
V6U69_RS09450 (V6U69_09440)	rpoE	2044172..2044747 (-)	576	WP_073685757.1	DNA-directed RNA polymerase subunit delta	-
V6U69_RS09455 (V6U69_09445)	tig	2044905..2046188 (-)	1284	WP_002889721.1	trigger factor	-
V6U69_RS09460 (V6U69_09450)	-	2046331..2047173 (+)	843	WP_073685758.1	mechanosensitive ion channel family protein	-
V6U69_RS09465 (V6U69_09455)	comX/sigX	2047288..2047785 (-)	498	WP_060973245.1	sigma factor	Regulator
V6U69_RS09470 (V6U69_09460)	-	2048279..2048956 (+)	678	WP_410533763.1	transposase	-
V6U69_RS09475 (V6U69_09465)	-	2048953..2049918 (+)	966	WP_410533765.1	IS3 family transposase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20039.81 Da
• Isoelectric Point: 4.9953

>NTDB_id=940811 V6U69_RS09465 WP_060973245.1 2047288..2047785(-) (comX/sigX) [Streptococcus salivarius strain KSS10]
MEQEVFVHAYEVVRPIVLKASRQYFIQLWDQADMEQEAMMTLYQLLEKFPELKSDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYIEISDIAFCLPNKELDAVDRLVYDEQLNAFRNQLSSEDSTKLDRLLAGECFRGRKKMIRELKFWMVDFDP
YNEDD

Nucleotide

• Length: 498 bp

>NTDB_id=940811 V6U69_RS09465 WP_060973245.1 2047288..2047785(-) (comX/sigX) [Streptococcus salivarius strain KSS10]
ATGGAACAAGAAGTTTTTGTTCACGCATATGAAGTTGTAAGGCCGATTGTACTTAAGGCTAGTAGACAATATTTCATCCA
ACTTTGGGACCAAGCTGATATGGAGCAAGAAGCTATGATGACGCTTTATCAGCTTTTAGAAAAGTTTCCTGAATTAAAGT
CTGATGATGATAAGTTGCGGCGATATTTTAAAACGAAATTTAGGAATAGACTTAATGATGAGGTTAGAAGGCAGGAGTCT
GTAAAACGACAAGCTAATCGACAATGTTATATCGAAATTTCAGATATTGCTTTTTGTCTCCCAAATAAAGAGTTAGATGC
TGTTGATAGGCTTGTTTATGACGAGCAGCTTAATGCTTTCCGTAATCAGTTGTCTTCGGAAGATTCTACTAAGTTAGACC
GTTTGCTAGCTGGGGAGTGTTTTAGAGGTCGAAAAAAGATGATTCGAGAGTTAAAATTTTGGATGGTTGATTTTGATCCT
TACAATGAAGATGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2W1I7B4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus salivarius strain HSISS4	99.394	100	0.994
comX	Streptococcus salivarius SK126	98.788	100	0.988
comX	Streptococcus thermophilus LMD-9	89.697	100	0.897
comX	Streptococcus thermophilus LMG 18311	89.697	100	0.897
comX	Streptococcus sobrinus strain NIDR 6715-7	40.606	100	0.406
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	42.581	93.939	0.4
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	42.581	93.939	0.4
comX/sigX	Streptococcus mutans UA159	41.667	94.545	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.026	94.545	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37