Detailed information NTG0895794

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4704_RS04535
• Genome accession: NZ_CP137109
• Coordinates: 853702..854028 (-)
• Length: 108 a.a.
• NCBI ID: WP_000738638.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11012
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 848702..859028

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4704_RS04490	rnpA	848726..849097 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R4704_RS04495	-	849114..849245 (-)	132	WP_000768904.1	hypothetical protein	-
R4704_RS04500	-	849246..850436 (-)	1191	WP_000167766.1	acetate kinase	-
R4704_RS04505	comYH	850487..851440 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
R4704_RS04510	-	851501..852088 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
R4704_RS04515	comGG/cglG	852225..852638 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4704_RS04520	comGF/cglF	852616..853077 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4704_RS04525	comGE/cglE	853040..853342 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4704_RS04530	comGD/cglD	853305..853709 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4704_RS04535	comGC/cglC	853702..854028 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
R4704_RS04540	comGB/cglB	854030..855046 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4704_RS04545	comGA/cglA/cilD	854994..855935 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
R4704_RS04550	-	856011..856376 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4704_RS04555	-	856527..857585 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4704_RS04560	nagA	857748..858899 (-)	1152	WP_033705218.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12173.35 Da
• Isoelectric Point: 10.0523

>NTDB_id=895794 R4704_RS04535 WP_000738638.1 853702..854028(-) (comGC/cglC) [Streptococcus pneumoniae strain 11012]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=895794 R4704_RS04535 WP_000738638.1 853702..854028(-) (comGC/cglC) [Streptococcus pneumoniae strain 11012]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae Rx1	98.148	100	0.981
comGC/cglC	Streptococcus pneumoniae D39	98.148	100	0.981
comGC/cglC	Streptococcus pneumoniae R6	98.148	100	0.981
comGC/cglC	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comGC/cglC	Streptococcus mitis SK321	94.444	100	0.944
comGC/cglC	Streptococcus mitis NCTC 12261	93.137	94.444	0.88
comYC	Streptococcus gordonii str. Challis substr. CH1	72.917	88.889	0.648
comYC	Streptococcus mutans UA140	63.725	94.444	0.602
comYC	Streptococcus mutans UA159	63.725	94.444	0.602
comYC	Streptococcus suis isolate S10	70.37	75	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comGC	Staphylococcus aureus MW2	50	79.63	0.398
comGC	Staphylococcus aureus N315	50	79.63	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361