Detailed information NTG0895795

Bioinformatically predicted

Overview

• Name: comGB/cglB
• Type: Machinery gene
• Locus tag: R4704_RS04540
• Genome accession: NZ_CP137109
• Coordinates: 854030..855046 (-)
• Length: 338 a.a.
• NCBI ID: WP_013193332.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11012
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 849030..860046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4704_RS04495	-	849114..849245 (-)	132	WP_000768904.1	hypothetical protein	-
R4704_RS04500	-	849246..850436 (-)	1191	WP_000167766.1	acetate kinase	-
R4704_RS04505	comYH	850487..851440 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
R4704_RS04510	-	851501..852088 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
R4704_RS04515	comGG/cglG	852225..852638 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4704_RS04520	comGF/cglF	852616..853077 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4704_RS04525	comGE/cglE	853040..853342 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4704_RS04530	comGD/cglD	853305..853709 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4704_RS04535	comGC/cglC	853702..854028 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
R4704_RS04540	comGB/cglB	854030..855046 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4704_RS04545	comGA/cglA/cilD	854994..855935 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
R4704_RS04550	-	856011..856376 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4704_RS04555	-	856527..857585 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4704_RS04560	nagA	857748..858899 (-)	1152	WP_033705218.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 338 a.a.
• Molecular weight: 38524.60 Da
• Isoelectric Point: 9.6162

>NTDB_id=895795 R4704_RS04540 WP_013193332.1 854030..855046(-) (comGB/cglB) [Streptococcus pneumoniae strain 11012]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide

• Length: 1017 bp

>NTDB_id=895795 R4704_RS04540 WP_013193332.1 854030..855046(-) (comGB/cglB) [Streptococcus pneumoniae strain 11012]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (24-141)

• Type II secretion system (T2SS), protein F (T2SSF) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB/cglB	Streptococcus pneumoniae Rx1	99.112	100	0.991
comGB/cglB	Streptococcus pneumoniae D39	99.112	100	0.991
comGB/cglB	Streptococcus pneumoniae R6	99.112	100	0.991
comGB/cglB	Streptococcus pneumoniae TIGR4	99.112	100	0.991
comGB/cglB	Streptococcus mitis SK321	94.97	100	0.95
comGB/cglB	Streptococcus mitis NCTC 12261	94.379	100	0.944
comYB	Streptococcus gordonii str. Challis substr. CH1	70.833	99.408	0.704
comYB	Streptococcus mutans UA140	58.176	94.083	0.547
comYB	Streptococcus mutans UA159	58.176	94.083	0.547
comGB	Lactococcus lactis subsp. cremoris KW2	50.898	98.817	0.503