Detailed information NTG0895408

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4708_RS06530
• Genome accession: NZ_CP137104
• Coordinates: 1289414..1289740 (+)
• Length: 108 a.a.
• NCBI ID: WP_000738650.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LM
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1284414..1294740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4708_RS06505	nagA	1284543..1285694 (+)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
R4708_RS06510	-	1285857..1286915 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4708_RS06515	-	1287066..1287431 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4708_RS06520	comGA/cglA/cilD	1287507..1288448 (+)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
R4708_RS06525	comGB/cglB	1288396..1289412 (+)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4708_RS06530	comGC/cglC	1289414..1289740 (+)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
R4708_RS06535	comGD/cglD	1289733..1290137 (+)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4708_RS06540	comGE/cglE	1290100..1290402 (+)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4708_RS06545	comGF/cglF	1290365..1290826 (+)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4708_RS06550	comGG/cglG	1290804..1291217 (+)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4708_RS06555	-	1291354..1291941 (+)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
R4708_RS06560	comYH	1292002..1292955 (+)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
R4708_RS06565	-	1293006..1294196 (+)	1191	WP_000167766.1	acetate kinase	-
R4708_RS06570	-	1294197..1294328 (+)	132	WP_000768904.1	hypothetical protein	-
R4708_RS06575	rnpA	1294345..1294716 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12189.35 Da
• Isoelectric Point: 10.0523

>NTDB_id=895408 R4708_RS06530 WP_000738650.1 1289414..1289740(+) (comGC/cglC) [Streptococcus pneumoniae strain LM]
MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=895408 R4708_RS06530 WP_000738650.1 1289414..1289740(+) (comGC/cglC) [Streptococcus pneumoniae strain LM]
ATGAAAAAAATGATGACATTCTTGAAAAAATCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae Rx1	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae D39	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae R6	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comGC/cglC	Streptococcus mitis SK321	93.519	100	0.935
comGC/cglC	Streptococcus mitis NCTC 12261	92.157	94.444	0.87
comYC	Streptococcus gordonii str. Challis substr. CH1	72.917	88.889	0.648
comYC	Streptococcus mutans UA140	63.725	94.444	0.602
comYC	Streptococcus mutans UA159	63.725	94.444	0.602
comYC	Streptococcus suis isolate S10	70.37	75	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comGC	Staphylococcus aureus MW2	50	79.63	0.398
comGC	Staphylococcus aureus N315	50	79.63	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361