Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4708_RS06560 Genome accession   NZ_CP137104
Coordinates   1292002..1292955 (+) Length   317 a.a.
NCBI ID   WP_000345119.1    Uniprot ID   A0A0T7TMT7
Organism   Streptococcus pneumoniae strain LM     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1287002..1297955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS06515 - 1287066..1287431 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4708_RS06520 comGA/cglA/cilD 1287507..1288448 (+) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  R4708_RS06525 comGB/cglB 1288396..1289412 (+) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4708_RS06530 comGC/cglC 1289414..1289740 (+) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  R4708_RS06535 comGD/cglD 1289733..1290137 (+) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4708_RS06540 comGE/cglE 1290100..1290402 (+) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4708_RS06545 comGF/cglF 1290365..1290826 (+) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4708_RS06550 comGG/cglG 1290804..1291217 (+) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4708_RS06555 - 1291354..1291941 (+) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R4708_RS06560 comYH 1292002..1292955 (+) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  R4708_RS06565 - 1293006..1294196 (+) 1191 WP_000167766.1 acetate kinase -
  R4708_RS06570 - 1294197..1294328 (+) 132 WP_000768904.1 hypothetical protein -
  R4708_RS06575 rnpA 1294345..1294716 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4708_RS06580 - 1294691..1295515 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  R4708_RS06585 jag 1295534..1296520 (+) 987 WP_000260019.1 RNA-binding cell elongation regulator Jag/EloR -
  R4708_RS06590 - 1296571..1297194 (+) 624 WP_000932633.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35746.93 Da        Isoelectric Point: 4.2434

>NTDB_id=895413 R4708_RS06560 WP_000345119.1 1292002..1292955(+) (comYH) [Streptococcus pneumoniae strain LM]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895413 R4708_RS06560 WP_000345119.1 1292002..1292955(+) (comYH) [Streptococcus pneumoniae strain LM]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T7TMT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533