Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD/cglD   Type   Machinery gene
Locus tag   R4708_RS06535 Genome accession   NZ_CP137104
Coordinates   1289733..1290137 (+) Length   134 a.a.
NCBI ID   WP_000588005.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1284733..1295137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS06510 - 1285857..1286915 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R4708_RS06515 - 1287066..1287431 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4708_RS06520 comGA/cglA/cilD 1287507..1288448 (+) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  R4708_RS06525 comGB/cglB 1288396..1289412 (+) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4708_RS06530 comGC/cglC 1289414..1289740 (+) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  R4708_RS06535 comGD/cglD 1289733..1290137 (+) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4708_RS06540 comGE/cglE 1290100..1290402 (+) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4708_RS06545 comGF/cglF 1290365..1290826 (+) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4708_RS06550 comGG/cglG 1290804..1291217 (+) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4708_RS06555 - 1291354..1291941 (+) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R4708_RS06560 comYH 1292002..1292955 (+) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  R4708_RS06565 - 1293006..1294196 (+) 1191 WP_000167766.1 acetate kinase -
  R4708_RS06570 - 1294197..1294328 (+) 132 WP_000768904.1 hypothetical protein -
  R4708_RS06575 rnpA 1294345..1294716 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 14636.81 Da        Isoelectric Point: 10.2164

>NTDB_id=895409 R4708_RS06535 WP_000588005.1 1289733..1290137(+) (comGD/cglD) [Streptococcus pneumoniae strain LM]
MIKAFTMLESLLALSLVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPV
PKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide


Download         Length: 405 bp        

>NTDB_id=895409 R4708_RS06535 WP_000588005.1 1289733..1290137(+) (comGD/cglD) [Streptococcus pneumoniae strain LM]
ATGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGCTTTGAGTCTTGTGAGTATCCTTGCCTTGGGCTTGTCCGGCTC
TGTTCAGTCCACTTTTGCGGCAGTAGAGGAACAGATTTTCTTTATGGAGTTTGAAGAACTCTATCGGGAAACCCAAAAAC
GCAGTGTAGCCAGTCAGCAAAAGACTAGTCTGAACTTAGATGGGCAGACGATTAGCAATGGCAGTCAAAAGTTGCCAGTC
CCTAAAGGAATTCAGGCCCCATCAGGCCAAAGTATTACATTTGACCGTGCTGGGGGCAATTCGTCCCTGGCTAAGGTTGA
ATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATGGAAAAATTAAACGCATTAAGGAAACAAAAA
ATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus pneumoniae TIGR4

97.015

100

0.97
  comGD/cglD Streptococcus pneumoniae Rx1

96.269

100

0.963
  comGD/cglD Streptococcus pneumoniae D39

96.269

100

0.963
  comGD/cglD Streptococcus pneumoniae R6

96.269

100

0.963
  comGD/cglD Streptococcus mitis NCTC 12261

96.241

99.254

0.955
  comGD/cglD Streptococcus mitis SK321

95.522

100

0.955
  comYD Streptococcus gordonii str. Challis substr. CH1

59.055

94.776

0.56
  comYD Streptococcus mutans UA140

50

95.522

0.478
  comYD Streptococcus mutans UA159

50

95.522

0.478