Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   RSK81_RS11565 Genome accession   NZ_CP135591
Coordinates   2337375..2338316 (-) Length   313 a.a.
NCBI ID   WP_315686885.1    Uniprot ID   A0AA96NLV2
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2332375..2343316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS11530 (RSK81_11530) comYH 2333600..2334565 (-) 966 WP_314831042.1 class I SAM-dependent methyltransferase Machinery gene
  RSK81_RS11535 (RSK81_11535) comGG 2334647..2335039 (-) 393 WP_048771947.1 competence type IV pilus minor pilin ComGG -
  RSK81_RS11540 (RSK81_11540) comGF/cglF 2335020..2335457 (-) 438 WP_002927109.1 competence type IV pilus minor pilin ComGF Machinery gene
  RSK81_RS11545 (RSK81_11545) comGE/cglE 2335441..2335734 (-) 294 WP_002911065.1 competence type IV pilus minor pilin ComGE Machinery gene
  RSK81_RS11550 (RSK81_11550) comYD 2335700..2336134 (-) 435 WP_002934686.1 competence type IV pilus minor pilin ComGD Machinery gene
  RSK81_RS11555 (RSK81_11555) comYC 2336094..2336411 (-) 318 WP_002927120.1 competence type IV pilus major pilin ComGC Machinery gene
  RSK81_RS11560 (RSK81_11560) comYB 2336411..2337445 (-) 1035 WP_260469178.1 competence type IV pilus assembly protein ComGB Machinery gene
  RSK81_RS11565 (RSK81_11565) comYA 2337375..2338316 (-) 942 WP_315686885.1 competence type IV pilus ATPase ComGA Machinery gene
  RSK81_RS11570 (RSK81_11570) - 2338446..2338826 (-) 381 WP_002901723.1 DUF1033 family protein -
  RSK81_RS11575 (RSK81_11575) - 2339145..2340251 (-) 1107 WP_002923025.1 glycosyl hydrolase family 8 -
  RSK81_RS11580 (RSK81_11580) - 2340260..2341570 (-) 1311 WP_002901729.1 glycosyltransferase family 2 protein -
  RSK81_RS11585 (RSK81_11585) - 2341563..2341706 (-) 144 WP_002896778.1 hypothetical protein -
  RSK81_RS11590 (RSK81_11590) - 2341718..2342506 (-) 789 WP_002896779.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35969.23 Da        Isoelectric Point: 5.9428

>NTDB_id=887060 RSK81_RS11565 WP_315686885.1 2337375..2338316(-) (comYA) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKLSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELDVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=887060 RSK81_RS11565 WP_315686885.1 2337375..2338316(-) (comYA) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGGTTCAAGAAATTGCAAAAGAAATGATTAGGCAGGCTCGGCAAGAGGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGTTTTATAAAGACTTATGATTTCGAGCTTCTGTCAGCTG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTTGGGTCTTGCGATTATGAC
TGCGAGGAAGCCAAGCTTTCAATCCGGCTGTCGACAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTTATCCGACTCCT
TCATGACGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGCAAGAAAATTCAGGCTCGCGGCCTCT
ATCTATTCTCAGGACCAGTCGGCAGCGGCAAGACGACCTTGATGTATCATTTGGCTCAGCTCAAATTTTCTGGCCAGCAG
GTTATGTCAATTGAAGATCCGGTTGAAATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGACAGTCTGATTAAGCTGTCTCTGCGACATCGGCCGGATCTCTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGGGCAGTGGTTCGGGCAAGTTTGACCGGAGCTACGGTCTTTTCAACGATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGGCTTTTGGAATTAGACGTTAGTGAGGACGAGCTAAGAATGGTGCTTCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACAGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.323

99.042

0.796
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.76

100

0.748
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.441

100

0.744
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.385

99.681

0.652
  comYA Streptococcus mutans UA159

65.273

99.361

0.649
  comYA Streptococcus mutans UA140

65.273

99.361

0.649
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

40.647

88.818

0.361