Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   RIN70_RS01165 Genome accession   NZ_CP134147
Coordinates   202062..203003 (+) Length   313 a.a.
NCBI ID   WP_155124982.1    Uniprot ID   -
Organism   Streptococcus parasanguinis strain 30.8.10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 197062..208003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIN70_RS01140 (RIN70_01140) - 198012..198800 (+) 789 WP_195623581.1 hypothetical protein -
  RIN70_RS01145 (RIN70_01145) - 198810..198950 (+) 141 WP_003004308.1 hypothetical protein -
  RIN70_RS01150 (RIN70_01150) - 198943..200253 (+) 1311 WP_195423844.1 glycosyltransferase -
  RIN70_RS01155 (RIN70_01155) - 200262..201365 (+) 1104 WP_155124981.1 glycosyl hydrolase family 8 -
  RIN70_RS01160 (RIN70_01160) - 201585..201974 (+) 390 WP_049505981.1 DUF1033 family protein -
  RIN70_RS01165 (RIN70_01165) comYA 202062..203003 (+) 942 WP_155124982.1 competence type IV pilus ATPase ComGA Machinery gene
  RIN70_RS01170 (RIN70_01170) comYB 202936..203967 (+) 1032 WP_195623587.1 competence type IV pilus assembly protein ComGB Machinery gene
  RIN70_RS01175 (RIN70_01175) comYC 203964..204281 (+) 318 WP_023919650.1 competence type IV pilus major pilin ComGC Machinery gene
  RIN70_RS01180 (RIN70_01180) comYD 204271..204675 (+) 405 WP_134974548.1 competence type IV pilus minor pilin ComGD Machinery gene
  RIN70_RS01185 (RIN70_01185) comGE 204641..204928 (+) 288 WP_049472874.1 competence type IV pilus minor pilin ComGE -
  RIN70_RS01190 (RIN70_01190) comGF/cglF 204918..205370 (+) 453 WP_049472872.1 competence type IV pilus minor pilin ComGF Machinery gene
  RIN70_RS01195 (RIN70_01195) comGG 205357..205791 (+) 435 WP_313790620.1 competence type IV pilus minor pilin ComGG -
  RIN70_RS01200 (RIN70_01200) comYH 205822..206775 (+) 954 WP_118397210.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35864.23 Da        Isoelectric Point: 5.9987

>NTDB_id=878836 RIN70_RS01165 WP_155124982.1 202062..203003(+) (comYA) [Streptococcus parasanguinis strain 30.8.10]
MVQEIAKKLIRMGKKEEAQDLYFIPRREEYQVFMRVGDERRFVQSFPFEEMTAMISHFKFVAGMNVGEKRRSQLGSCDYP
LEDGLVSIRLSTVGDYRGYESLVIRLLHDEERELRFWFDQLPELKKKLAGRGLYLFAGPVGSGKTTLMHALAQECFADQQ
VMSIEDPVEIKQDNMLQLQLNDQIGMTYDNLIKLSLRHRPDLLIIGEIRDKETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVSEEELKIVLQGICYQRLIAGGGVVDFATENYQEHSASRWNQQMDLLAQSGYIQLAQAQAEKIIYN

Nucleotide


Download         Length: 942 bp        

>NTDB_id=878836 RIN70_RS01165 WP_155124982.1 202062..203003(+) (comYA) [Streptococcus parasanguinis strain 30.8.10]
ATGGTTCAAGAAATTGCAAAAAAATTGATTCGTATGGGAAAAAAAGAAGAAGCCCAGGATCTCTACTTTATCCCTCGGAG
AGAGGAGTACCAGGTTTTTATGAGGGTTGGAGATGAGAGGCGCTTTGTACAATCCTTCCCTTTTGAGGAGATGACGGCTA
TGATCAGCCACTTTAAGTTCGTAGCAGGCATGAACGTGGGAGAAAAAAGGCGGAGCCAGCTAGGGTCGTGTGATTACCCT
CTGGAGGATGGGCTGGTTTCGATTCGCTTGTCGACGGTGGGGGATTATCGTGGCTATGAAAGCTTGGTTATTCGGCTCTT
GCATGATGAGGAACGCGAATTGCGTTTTTGGTTTGATCAGCTACCTGAGTTGAAGAAGAAATTGGCTGGTCGTGGGCTCT
ATCTCTTTGCGGGCCCTGTTGGTTCGGGAAAGACCACTCTCATGCATGCTTTGGCGCAAGAGTGCTTTGCGGACCAGCAA
GTCATGTCCATTGAGGATCCTGTCGAGATCAAGCAGGATAATATGTTACAGCTTCAGCTGAACGACCAGATCGGCATGAC
CTATGACAACCTGATCAAACTCTCCTTACGTCATCGGCCGGACCTTCTCATCATTGGGGAAATTCGAGATAAGGAAACAG
CTCGTGCAGTCGTACGAGCTAGTTTGACAGGGGTCACAGTCTTCTCTACTATTCATGCCAAGAGCGTTCGAGGTGTTTAT
GAGAGGCTCTTAGAGCTTGGAGTGAGTGAGGAAGAGCTCAAGATTGTTTTACAAGGTATTTGCTACCAACGATTAATTGC
AGGAGGAGGTGTTGTCGATTTTGCGACGGAAAACTACCAAGAACACTCAGCCAGCCGCTGGAACCAACAAATGGATCTCT
TGGCTCAATCGGGATATATCCAGCTGGCTCAGGCACAAGCCGAAAAAATTATCTACAACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(15-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

74.194

99.042

0.735
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

71.885

100

0.719
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

71.565

100

0.716
  comGA/cglA/cilD Streptococcus pneumoniae D39

71.565

100

0.716
  comGA/cglA/cilD Streptococcus pneumoniae R6

71.565

100

0.716
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

71.565

100

0.716
  comYA Streptococcus mutans UA159

63.987

99.361

0.636
  comYA Streptococcus mutans UA140

63.987

99.361

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.286

100

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.446

88.818

0.377