Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   PXH68_RS00635 Genome accession   NZ_CP118733
Coordinates   100296..101234 (+) Length   312 a.a.
NCBI ID   WP_172015367.1    Uniprot ID   A0AA96VFB6
Organism   Streptococcus suivaginalis strain 29896     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 95296..106234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXH68_RS00625 (PXH68_00625) - 98873..99232 (+) 360 WP_105117566.1 DUF1033 family protein -
  PXH68_RS00630 (PXH68_00630) - 99242..100210 (-) 969 WP_248028796.1 S66 peptidase family protein -
  PXH68_RS00635 (PXH68_00635) comYA 100296..101234 (+) 939 WP_172015367.1 competence type IV pilus ATPase ComGA Machinery gene
  PXH68_RS00640 (PXH68_00640) comYB 101158..102195 (+) 1038 WP_248028795.1 competence type IV pilus assembly protein ComGB Machinery gene
  PXH68_RS00645 (PXH68_00645) comYC 102197..102478 (+) 282 WP_172015368.1 competence type IV pilus major pilin ComGC Machinery gene
  PXH68_RS00650 (PXH68_00650) comGD 102459..102866 (+) 408 WP_172015369.1 competence type IV pilus minor pilin ComGD -
  PXH68_RS00655 (PXH68_00655) comYE 102838..103131 (+) 294 WP_024385126.1 competence type IV pilus minor pilin ComGE Machinery gene
  PXH68_RS00660 (PXH68_00660) comGF/cglF 103118..103552 (+) 435 WP_044676306.1 competence type IV pilus minor pilin ComGF Machinery gene
  PXH68_RS00665 (PXH68_00665) comGG 103530..104051 (+) 522 WP_172015370.1 competence type IV pilus minor pilin ComGG -
  PXH68_RS00670 (PXH68_00670) comYH 104101..105054 (+) 954 WP_172015371.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35128.97 Da        Isoelectric Point: 5.9423

>NTDB_id=794607 PXH68_RS00635 WP_172015367.1 100296..101234(+) (comYA) [Streptococcus suivaginalis strain 29896]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADRWNAQIDRLFAAGHISLRQAETEKIAF

Nucleotide


Download         Length: 939 bp        

>NTDB_id=794607 PXH68_RS00635 WP_172015367.1 100296..101234(+) (comYA) [Streptococcus suivaginalis strain 29896]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTGGTTCCTCGTGG
TCAGGGCTACCAAGTCTACCATCGTATCATGGACGAGCGAGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGCTTAAATGTCGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGATTATGAT
TATGGTAGCGGAGAGATTTCGCTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATTGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACAGGAGCTACCGTTTTCTCAACAGTTCATGCACGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAACAATGCCCTTCAAGGGATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCGGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCTTTTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

99.359

0.683
  comYA Streptococcus mutans UA159

67.524

99.679

0.673
  comYA Streptococcus mutans UA140

67.524

99.679

0.673
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.064

100

0.651
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.064

100

0.651
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.064

100

0.651
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.064

100

0.651
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.064

100

0.651
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.359

0.644
  comGA Lactococcus lactis subsp. cremoris KW2

54.167

100

0.542
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

88.782

0.369