Detailed information NTG0714825

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NQZ93_RS00760
• Genome accession: NZ_CP102141
• Coordinates: 120820..121101 (+)
• Length: 93 a.a.
• NCBI ID: WP_024382124.1
• Uniprot ID: A0A075SBB9
• Organism: Streptococcus suis strain DNR48
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 115820..126101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ93_RS00740 (NQZ93_00740)	-	117483..117848 (+)	366	WP_002936568.1	DUF1033 family protein	-
NQZ93_RS00745 (NQZ93_00745)	-	117883..118833 (-)	951	WP_257115308.1	S66 peptidase family protein	-
NQZ93_RS00750 (NQZ93_00750)	comYA	118919..119869 (+)	951	WP_024382125.1	competence type IV pilus ATPase ComGA	Machinery gene
NQZ93_RS00755 (NQZ93_00755)	comYB	119781..120818 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQZ93_RS00760 (NQZ93_00760)	comYC	120820..121101 (+)	282	WP_024382124.1	competence type IV pilus major pilin ComGC	Machinery gene
NQZ93_RS00765 (NQZ93_00765)	comGD	121082..121489 (+)	408	WP_024382123.1	competence type IV pilus minor pilin ComGD	-
NQZ93_RS00770 (NQZ93_00770)	comYE	121461..121754 (+)	294	WP_024382122.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQZ93_RS00775 (NQZ93_00775)	comGF/cglF	121741..122175 (+)	435	WP_024382121.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQZ93_RS00780 (NQZ93_00780)	comGG	122153..122563 (+)	411	WP_024382120.1	competence type IV pilus minor pilin ComGG	-
NQZ93_RS00785 (NQZ93_00785)	comYH	122620..123573 (+)	954	WP_257115309.1	class I SAM-dependent methyltransferase	Machinery gene
NQZ93_RS00790 (NQZ93_00790)	-	123623..124810 (+)	1188	WP_024382118.1	acetate kinase	-
NQZ93_RS00795 (NQZ93_00795)	-	125125..125676 (+)	552	WP_024382117.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10377.37 Da
• Isoelectric Point: 9.3901

>NTDB_id=714825 NQZ93_RS00760 WP_024382124.1 120820..121101(+) (comYC) [Streptococcus suis strain DNR48]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAKAKK

Nucleotide

• Length: 282 bp

>NTDB_id=714825 NQZ93_RS00760 WP_024382124.1 120820..121101(+) (comYC) [Streptococcus suis strain DNR48]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTAAGGCGAAGAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A075SBB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus gordonii str. Challis substr. CH1	62.921	95.699	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Latilactobacillus sakei subsp. sakei 23K	44.706	91.398	0.409
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398