Detailed information NTG0068320

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: SNAG_RS01185
• Genome accession: NZ_AP017652
• Coordinates: 206800..207123 (+)
• Length: 107 a.a.
• NCBI ID: WP_001037925.1
• Uniprot ID: -
• Organism: Streptococcus sp. NPS 308
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 201800..212123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SNAG_RS01165 (SNAG_0235)	nagA	203162..204313 (+)	1152	WP_096405914.1	N-acetylglucosamine-6-phosphate deacetylase	-
SNAG_RS01170 (SNAG_0236)	-	204465..204830 (+)	366	WP_096405916.1	DUF1033 family protein	-
SNAG_RS01175 (SNAG_0237)	comGA/cglA/cilD	204893..205834 (+)	942	WP_096405917.1	competence type IV pilus ATPase ComGA	Machinery gene
SNAG_RS01180 (SNAG_0238)	comGB/cglB	205782..206798 (+)	1017	WP_096405919.1	competence type IV pilus assembly protein ComGB	Machinery gene
SNAG_RS01185 (SNAG_0239)	comGC/cglC	206800..207123 (+)	324	WP_001037925.1	competence type IV pilus major pilin ComGC	Machinery gene
SNAG_RS01190 (SNAG_0240)	comGD/cglD	207086..207520 (+)	435	WP_172842371.1	competence type IV pilus minor pilin ComGD	Machinery gene
SNAG_RS01195 (SNAG_0241)	comGE/cglE	207483..207785 (+)	303	WP_172842372.1	competence type IV pilus minor pilin ComGE	Machinery gene
SNAG_RS01200 (SNAG_0242)	comGF/cglF	207748..208209 (+)	462	WP_096405922.1	competence type IV pilus minor pilin ComGF	Machinery gene
SNAG_RS01205 (SNAG_0243)	comGG/cglG	208187..208600 (+)	414	WP_096405924.1	competence type IV pilus minor pilin ComGG	Machinery gene
SNAG_RS01210 (SNAG_0244)	-	208633..209223 (+)	591	WP_172842373.1	class I SAM-dependent methyltransferase	-
SNAG_RS01215 (SNAG_0245)	comYH	209282..210235 (+)	954	WP_096405925.1	class I SAM-dependent methyltransferase	Machinery gene
SNAG_RS01220 (SNAG_0246)	-	210285..211475 (+)	1191	WP_000167798.1	acetate kinase	-
SNAG_RS01225 (SNAG_0247)	rnpA	211635..212006 (+)	372	WP_000739254.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11905.02 Da
• Isoelectric Point: 10.0754

>NTDB_id=68320 SNAG_RS01185 WP_001037925.1 206800..207123(+) (comGC/cglC) [Streptococcus sp. NPS 308]
MNKLMTKLKKAKVQAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYRLDKNDDATLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=68320 SNAG_RS01185 WP_001037925.1 206800..207123(+) (comGC/cglC) [Streptococcus sp. NPS 308]
ATGAACAAACTCATGACAAAATTAAAAAAAGCCAAAGTTCAAGCTTTCACTCTGGTAGAGATGTTAGTCGTCTTGCTCAT
CATCAGCGTTCTTCTCTTGCTCTTTGTACCCAATTTGACCAAGCAAAAGGATGCCGTAGATGACAAAGGAAAAGCTGCTG
TTGTCAAGGTGGTGGAAAGTCAGGCAGAACTTTATCGTTTGGATAAAAATGATGATGCTACCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCCAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACGGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	88.785	100	0.888
comGC/cglC	Streptococcus mitis SK321	85.859	92.523	0.794
comGC/cglC	Streptococcus pneumoniae Rx1	83.838	92.523	0.776
comGC/cglC	Streptococcus pneumoniae D39	83.838	92.523	0.776
comGC/cglC	Streptococcus pneumoniae R6	83.838	92.523	0.776
comGC/cglC	Streptococcus pneumoniae TIGR4	82.828	92.523	0.766
comYC	Streptococcus gordonii str. Challis substr. CH1	68.571	98.131	0.673
comYC	Streptococcus mutans UA140	72.165	90.654	0.654
comYC	Streptococcus mutans UA159	72.165	90.654	0.654
comYC	Streptococcus suis isolate S10	67.045	82.243	0.551
comGC	Lactococcus lactis subsp. cremoris KW2	56.863	95.327	0.542
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364