Detailed information NTG0068323

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SNAG_RS01200
• Genome accession: NZ_AP017652
• Coordinates: 207748..208209 (+)
• Length: 153 a.a.
• NCBI ID: WP_096405922.1
• Uniprot ID: -
• Organism: Streptococcus sp. NPS 308
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 202748..213209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SNAG_RS01165 (SNAG_0235)	nagA	203162..204313 (+)	1152	WP_096405914.1	N-acetylglucosamine-6-phosphate deacetylase	-
SNAG_RS01170 (SNAG_0236)	-	204465..204830 (+)	366	WP_096405916.1	DUF1033 family protein	-
SNAG_RS01175 (SNAG_0237)	comGA/cglA/cilD	204893..205834 (+)	942	WP_096405917.1	competence type IV pilus ATPase ComGA	Machinery gene
SNAG_RS01180 (SNAG_0238)	comGB/cglB	205782..206798 (+)	1017	WP_096405919.1	competence type IV pilus assembly protein ComGB	Machinery gene
SNAG_RS01185 (SNAG_0239)	comGC/cglC	206800..207123 (+)	324	WP_001037925.1	competence type IV pilus major pilin ComGC	Machinery gene
SNAG_RS01190 (SNAG_0240)	comGD/cglD	207086..207520 (+)	435	WP_172842371.1	competence type IV pilus minor pilin ComGD	Machinery gene
SNAG_RS01195 (SNAG_0241)	comGE/cglE	207483..207785 (+)	303	WP_172842372.1	competence type IV pilus minor pilin ComGE	Machinery gene
SNAG_RS01200 (SNAG_0242)	comGF/cglF	207748..208209 (+)	462	WP_096405922.1	competence type IV pilus minor pilin ComGF	Machinery gene
SNAG_RS01205 (SNAG_0243)	comGG/cglG	208187..208600 (+)	414	WP_096405924.1	competence type IV pilus minor pilin ComGG	Machinery gene
SNAG_RS01210 (SNAG_0244)	-	208633..209223 (+)	591	WP_172842373.1	class I SAM-dependent methyltransferase	-
SNAG_RS01215 (SNAG_0245)	comYH	209282..210235 (+)	954	WP_096405925.1	class I SAM-dependent methyltransferase	Machinery gene
SNAG_RS01220 (SNAG_0246)	-	210285..211475 (+)	1191	WP_000167798.1	acetate kinase	-
SNAG_RS01225 (SNAG_0247)	rnpA	211635..212006 (+)	372	WP_000739254.1	ribonuclease P protein component	-
SNAG_RS01230 (SNAG_0248)	-	211981..212808 (+)	828	WP_172842374.1	YidC/Oxa1 family membrane protein insertase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17870.52 Da
• Isoelectric Point: 9.5600

>NTDB_id=68323 SNAG_RS01200 WP_096405922.1 207748..208209(+) (comGF/cglF) [Streptococcus sp. NPS 308]
MVQRSYSTLKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLITEVRYQQQSEQKEWLLFVDQLEAELERSQFEKVEDN
RLYMKQDGKAIAMGTFKSDDFRKTDSSGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKAKS

Nucleotide

• Length: 462 bp

>NTDB_id=68323 SNAG_RS01200 WP_096405922.1 207748..208209(+) (comGF/cglF) [Streptococcus sp. NPS 308]
ATGGTTCAGAGAAGTTACTCGACCTTAAAGAGCAGTAAGGTAAGAGCTTTCACTCTTTTAGAATCTCTGATTGCCCTTAT
CGTCATTAGCGGTGGCTTGCTTCTCTTTCAAGCCATGAGTCAGCTCCTCATTACAGAAGTTCGCTATCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAGCTAGAGGCTGAGTTAGAGCGTTCGCAGTTTGAGAAGGTGGAAGACAAT
CGCCTCTATATGAAGCAAGACGGCAAGGCTATCGCTATGGGCACATTCAAATCGGATGATTTTCGAAAAACCGATAGCAG
TGGACGGGGTTACCAGCCGATGGTTTATGGCCTCAAATCAGCACAAATCACAGAGGATAATCAACTGGTTCGCTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAATTCATCTATCGTGTGGAAAAAGCAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (46-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis SK321	87.582	100	0.876
comGF/cglF	Streptococcus mitis NCTC 12261	86.275	100	0.863
comGF/cglF	Streptococcus pneumoniae Rx1	84.967	100	0.85
comGF/cglF	Streptococcus pneumoniae D39	84.967	100	0.85
comGF/cglF	Streptococcus pneumoniae R6	84.967	100	0.85
comGF/cglF	Streptococcus pneumoniae TIGR4	84.967	100	0.85
comGF	Lactococcus lactis subsp. cremoris KW2	40	91.503	0.366