Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SITYG_RS09120 Genome accession   NZ_AP014880
Coordinates   1792536..1793477 (-) Length   313 a.a.
NCBI ID   WP_096363208.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1787536..1798477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS09080 (SITYG_17980) - 1787587..1788786 (-) 1200 WP_009569506.1 acetate kinase -
  SITYG_RS09085 (SITYG_17990) comYH 1788833..1789786 (-) 954 WP_096363205.1 class I SAM-dependent methyltransferase Machinery gene
  SITYG_RS09090 (SITYG_18000) comGG 1789877..1790203 (-) 327 WP_020999196.1 competence type IV pilus minor pilin ComGG -
  SITYG_RS09095 (SITYG_18010) comGF/cglF 1790184..1790621 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SITYG_RS09100 (SITYG_18020) comGE/cglE 1790605..1790898 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  SITYG_RS09105 (SITYG_18030) comYD 1790870..1791298 (-) 429 WP_096363206.1 competence type IV pilus minor pilin ComGD Machinery gene
  SITYG_RS09110 (SITYG_18040) comYC 1791258..1791575 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SITYG_RS09115 (SITYG_18050) comYB 1791572..1792594 (-) 1023 WP_173672242.1 competence type IV pilus assembly protein ComGB Machinery gene
  SITYG_RS09120 (SITYG_18060) comYA 1792536..1793477 (-) 942 WP_096363208.1 competence type IV pilus ATPase ComGA Machinery gene
  SITYG_RS09125 (SITYG_18070) - 1793546..1793911 (-) 366 WP_009569514.1 DUF1033 family protein -
  SITYG_RS09130 (SITYG_18080) - 1794040..1794756 (-) 717 WP_009569515.1 TipC family immunity protein -
  SITYG_RS10700 (SITYG_18090) - 1794731..1796347 (-) 1617 WP_231870233.1 T7SS effector LXG polymorphic toxin -
  SITYG_RS09140 (SITYG_18100) glnA 1796543..1797889 (-) 1347 WP_021003260.1 type I glutamate--ammonia ligase -
  SITYG_RS09145 (SITYG_18110) - 1797928..1798287 (-) 360 WP_096363209.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36006.33 Da        Isoelectric Point: 7.4730

>NTDB_id=67287 SITYG_RS09120 WP_096363208.1 1792536..1793477(-) (comYA) [Streptococcus intermedius strain TYG1620]
MVQNIAQDIICQAKEKQAQDIYFIPKENSYELYMRIGDERRFIQQYAFEKMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YRDKKTSLRLSTVGDYRGYESLVIRLLHDEKAELKFWFAQIPELKGQLKQRGLYLFSGPVGSGKTTLMHQLAQERFADEQ
IMSIEDPVEIKQDRMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDTETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTDAELKIVLQGICYQRLIAKGGIVDFVSERYQEHDPSEWNRQIDQLYAAGHINLEQAKAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=67287 SITYG_RS09120 WP_096363208.1 1792536..1793477(-) (comYA) [Streptococcus intermedius strain TYG1620]
ATGGTTCAAAACATTGCACAAGATATTATTTGCCAAGCTAAGGAAAAACAGGCTCAAGATATTTATTTTATCCCAAAGGA
AAATAGTTATGAACTGTACATGAGAATTGGTGATGAGCGACGTTTTATACAACAGTATGCATTTGAAAAGATGGCAGCGG
TGATTAGTCATTTCAAATTTACCGCTGGGATGAATGTTGGTGAAAAACGTAGAAGCCAACTAGGGTCTTGTGATTATCAA
TACAGGGATAAGAAAACGTCACTGCGGTTGTCAACAGTAGGGGATTATCGCGGATATGAAAGTCTTGTAATTCGTTTATT
GCATGATGAAAAAGCAGAGTTGAAGTTTTGGTTTGCTCAAATTCCAGAGTTGAAAGGACAACTCAAGCAACGTGGACTTT
ATCTTTTTTCAGGACCGGTAGGGAGTGGCAAAACCACTCTTATGCATCAACTGGCTCAAGAACGTTTTGCCGATGAGCAA
ATCATGTCTATCGAAGATCCTGTTGAAATTAAGCAAGACAGAATGTTGCAATTGCAATTGAATGAAGCGATTGGCTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGACATCGTCCAGATTTATTGATTATTGGAGAAATTCGAGATACAGAAACAG
CACGGGCGGTTGTACGAGCCAGCTTGACAGGAGTGACGGTCTTTTCAACGATTCATGCTAAAAGTGTGCGAGGCGTTTAT
GAACGATTGCTAGAGTTGGGAGTGACAGACGCAGAGCTGAAAATTGTCTTGCAAGGTATTTGTTACCAACGTCTAATTGC
GAAAGGAGGAATAGTAGATTTTGTCAGTGAAAGGTATCAAGAACACGATCCAAGCGAATGGAATAGGCAAATTGATCAAC
TTTATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.323

99.042

0.796
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.226

99.042

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.629

82.748

0.361

Multiple sequence alignment