Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   L3475_RS09860 Genome accession   NZ_CP091451
Coordinates   1895983..1896309 (-) Length   108 a.a.
NCBI ID   WP_263275209.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 3238/09     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1890983..1901309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3475_RS09815 (L3475_09740) rnpA 1891007..1891378 (-) 372 WP_000739246.1 ribonuclease P protein component -
  L3475_RS09820 - 1891395..1891526 (-) 132 WP_000768904.1 hypothetical protein -
  L3475_RS09825 (L3475_09745) - 1891527..1892717 (-) 1191 WP_000167766.1 acetate kinase -
  L3475_RS09830 (L3475_09750) comYH 1892768..1893721 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  L3475_RS09835 (L3475_09755) - 1893782..1894369 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  L3475_RS09840 (L3475_09760) comGG/cglG 1894506..1894919 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  L3475_RS09845 (L3475_09765) comGF/cglF 1894897..1895358 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  L3475_RS09850 (L3475_09770) comGE/cglE 1895321..1895623 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  L3475_RS09855 (L3475_09775) comGD/cglD 1895586..1895990 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  L3475_RS09860 (L3475_09780) comGC/cglC 1895983..1896309 (-) 327 WP_263275209.1 comG operon protein ComGC Machinery gene
  L3475_RS09865 (L3475_09785) comGB/cglB 1896311..1897327 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  L3475_RS09870 (L3475_09790) comGA/cglA/cilD 1897275..1898216 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  L3475_RS09875 (L3475_09795) - 1898292..1898657 (-) 366 WP_000286415.1 DUF1033 family protein -
  L3475_RS09880 (L3475_09800) - 1898808..1899866 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  L3475_RS09885 (L3475_09805) nagA 1900029..1901180 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12237.44 Da        Isoelectric Point: 10.1213

>NTDB_id=651359 L3475_RS09860 WP_263275209.1 1895983..1896309(-) (comGC/cglC) [Streptococcus pneumoniae strain 3238/09]
MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
YGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=651359 L3475_RS09860 WP_263275209.1 1895983..1896309(-) (comGC/cglC) [Streptococcus pneumoniae strain 3238/09]
ATGAAAAAAATGATGACATTCTTGAAAAAATCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
TATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

91.176

94.444

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

72.917

88.889

0.648
  comYC Streptococcus mutans UA140

63.725

94.444

0.602
  comYC Streptococcus mutans UA159

63.725

94.444

0.602
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389