Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   N596_RS08115 Genome accession   NC_022584
Coordinates   1713185..1714144 (+) Length   319 a.a.
NCBI ID   WP_023027559.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1708185..1719144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS08095 (N596_08310) - 1709141..1709929 (+) 789 WP_023027556.1 hypothetical protein -
  N596_RS08100 (N596_08315) - 1710072..1711382 (+) 1311 WP_023027557.1 glycosyltransferase family 2 protein -
  N596_RS08105 (N596_08320) - 1711391..1712494 (+) 1104 WP_006595140.1 glycosyl hydrolase family 8 -
  N596_RS08110 (N596_08325) - 1712701..1713078 (+) 378 WP_023027558.1 DUF1033 family protein -
  N596_RS08115 (N596_08330) comYA 1713185..1714144 (+) 960 WP_023027559.1 competence type IV pilus ATPase ComGA Machinery gene
  N596_RS08120 (N596_08335) comYB 1714068..1715090 (+) 1023 WP_023027560.1 competence type IV pilus assembly protein ComGB Machinery gene
  N596_RS08125 (N596_08340) comGC/cglC 1715087..1715404 (+) 318 WP_023027561.1 competence type IV pilus major pilin ComGC Machinery gene
  N596_RS08130 (N596_08345) comGD/cglD 1715394..1715798 (+) 405 WP_243635769.1 competence type IV pilus minor pilin ComGD Machinery gene
  N596_RS08135 (N596_08350) comGE 1715764..1716057 (+) 294 WP_042361331.1 competence type IV pilus minor pilin ComGE -
  N596_RS08140 (N596_08355) comGF/cglF 1716041..1716493 (+) 453 WP_042361447.1 competence type IV pilus minor pilin ComGF Machinery gene
  N596_RS08145 (N596_08360) comGG 1716459..1716905 (+) 447 WP_006595132.1 competence type IV pilus minor pilin ComGG -
  N596_RS08150 (N596_08365) comYH 1716937..1717890 (+) 954 WP_042361332.1 class I SAM-dependent methyltransferase Machinery gene
  N596_RS08155 (N596_08370) - 1717939..1719135 (+) 1197 WP_023027566.1 acetate kinase -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 36342.55 Da        Isoelectric Point: 5.8892

>NTDB_id=62970 N596_RS08115 WP_023027559.1 1713185..1714144(+) (comYA) [Streptococcus ilei]
MVQEIAQSIIRMASSAEAQDIYFVPRASDYQLFLRVGDERRFIETYSQEQMVAVISHFKFMAGMNVGERRRSQLGSCDYS
LGDKVLSLRLSTVGDYRGYESLVIRLLHNEDRELRFWFDQLQELEEKVSKRGLYLFAGPVGSGKTTLMHALAKKKFSGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGMTYDSLIKLSLRHRPDLLLIGEIRDTETARAVIRASLTGVTVFSTIHAKSIPGVY
ERLLELGVSEEELRVVLQGICYQRLIKGGGVTDFVIQDYQNHSSQKWNQQIDTLYEAGHIELDQAQAEKIIDCQARACH

Nucleotide


Download         Length: 960 bp        

>NTDB_id=62970 N596_RS08115 WP_023027559.1 1713185..1714144(+) (comYA) [Streptococcus ilei]
ATGGTTCAAGAAATTGCACAATCCATTATTCGAATGGCCTCGAGTGCCGAAGCTCAGGATATTTATTTTGTTCCTCGAGC
GTCAGACTATCAGCTCTTTCTAAGGGTTGGGGATGAGAGACGGTTTATTGAGACTTATTCGCAAGAACAAATGGTAGCGG
TCATCAGCCATTTTAAATTTATGGCAGGGATGAACGTGGGGGAGAGGCGGAGGAGTCAGTTAGGCTCCTGTGACTATTCT
CTAGGAGATAAGGTCTTGTCCTTACGCTTGTCCACAGTGGGGGACTATAGGGGATATGAAAGTTTGGTCATTCGCCTGCT
CCACAATGAGGACCGGGAGCTCCGTTTCTGGTTCGATCAACTGCAAGAGCTAGAAGAGAAGGTGAGTAAGCGGGGGCTCT
ACTTATTTGCGGGTCCAGTCGGATCGGGGAAGACGACACTGATGCATGCCCTAGCCAAGAAAAAATTTTCGGGGCAACAA
GTCATGTCGATTGAAGATCCGGTAGAAATTAAGCAAGAAGAAATGCTGCAATTGCAACTCAATGAAGCGATTGGCATGAC
CTACGATAGCTTGATTAAACTTTCTTTGCGCCATCGTCCGGATCTTCTCCTTATCGGAGAAATACGCGACACGGAGACAG
CTCGTGCAGTTATTCGGGCTAGTCTGACAGGTGTGACAGTTTTTTCCACCATCCATGCCAAGAGCATTCCTGGGGTGTAC
GAACGCCTGTTGGAGTTGGGGGTGAGTGAGGAGGAGTTAAGGGTTGTTCTTCAAGGGATCTGTTACCAGCGTTTGATAAA
GGGAGGAGGTGTCACTGACTTTGTCATCCAAGATTACCAAAACCATTCCAGTCAAAAGTGGAACCAGCAAATTGATACAC
TTTATGAAGCGGGACATATTGAGTTGGATCAGGCGCAGGCCGAAAAAATTATCGATTGCCAAGCAAGAGCATGTCATTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

74.295

100

0.743
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

73.548

97.179

0.715
  comGA/cglA/cilD Streptococcus pneumoniae D39

72.903

97.179

0.708
  comGA/cglA/cilD Streptococcus pneumoniae R6

72.903

97.179

0.708
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

72.903

97.179

0.708
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

72.903

97.179

0.708
  comYA Streptococcus mutans UA159

65.176

98.119

0.64
  comYA Streptococcus mutans UA140

65.176

98.119

0.64
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.5

97.806

0.611
  comGA Lactococcus lactis subsp. cremoris KW2

55.696

99.06

0.552
  comGA Latilactobacillus sakei subsp. sakei 23K

41.877

86.834

0.364

Multiple sequence alignment