Detailed information NTG0062974

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: N596_RS08140
• Genome accession: NC_022584
• Coordinates: 1716041..1716493 (+)
• Length: 150 a.a.
• NCBI ID: WP_042361447.1
• Uniprot ID: -
• Organism: Streptococcus ilei
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1711041..1721493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N596_RS08105 (N596_08320)	-	1711391..1712494 (+)	1104	WP_006595140.1	glycosyl hydrolase family 8	-
N596_RS08110 (N596_08325)	-	1712701..1713078 (+)	378	WP_023027558.1	DUF1033 family protein	-
N596_RS08115 (N596_08330)	comYA	1713185..1714144 (+)	960	WP_023027559.1	competence type IV pilus ATPase ComGA	Machinery gene
N596_RS08120 (N596_08335)	comYB	1714068..1715090 (+)	1023	WP_023027560.1	competence type IV pilus assembly protein ComGB	Machinery gene
N596_RS08125 (N596_08340)	comGC/cglC	1715087..1715404 (+)	318	WP_023027561.1	competence type IV pilus major pilin ComGC	Machinery gene
N596_RS08130 (N596_08345)	comGD/cglD	1715394..1715798 (+)	405	WP_243635769.1	competence type IV pilus minor pilin ComGD	Machinery gene
N596_RS08135 (N596_08350)	comGE	1715764..1716057 (+)	294	WP_042361331.1	competence type IV pilus minor pilin ComGE	-
N596_RS08140 (N596_08355)	comGF/cglF	1716041..1716493 (+)	453	WP_042361447.1	competence type IV pilus minor pilin ComGF	Machinery gene
N596_RS08145 (N596_08360)	comGG	1716459..1716905 (+)	447	WP_006595132.1	competence type IV pilus minor pilin ComGG	-
N596_RS08150 (N596_08365)	comYH	1716937..1717890 (+)	954	WP_042361332.1	class I SAM-dependent methyltransferase	Machinery gene
N596_RS08155 (N596_08370)	-	1717939..1719135 (+)	1197	WP_023027566.1	acetate kinase	-
N596_RS08160 (N596_08375)	-	1719288..1719962 (+)	675	WP_258025867.1	CPBP family intramembrane glutamic endopeptidase	-
N596_RS08165 (N596_08380)	folP	1720121..1721077 (+)	957	WP_023027568.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 150 a.a.
• Molecular weight: 17062.69 Da
• Isoelectric Point: 4.8779

>NTDB_id=62974 N596_RS08140 WP_042361447.1 1716041..1716493(+) (comGF/cglF) [Streptococcus ilei]
MLKRNKVPAFTLLEALVALLVISGGLLVFQGLTSLLRQELQYQSQIKQEEWLLFQDQLDIELSRSQFEEVRDNKLYLVQD
QKPIAIGLAKGGDIRKTDATGRGYQPMIDGVESALIEKRGDLVSIQLRFAEGLEREVVYRVVEKDKKEAD

Nucleotide

• Length: 453 bp

>NTDB_id=62974 N596_RS08140 WP_042361447.1 1716041..1716493(+) (comGF/cglF) [Streptococcus ilei]
CTGTTGAAAAGAAATAAAGTTCCAGCCTTTACTTTACTGGAAGCCTTGGTTGCCCTGCTCGTCATTAGCGGTGGTTTATT
GGTGTTTCAAGGATTGACAAGCCTCTTGCGTCAAGAGCTCCAGTACCAAAGTCAAATCAAGCAAGAAGAGTGGTTGCTCT
TTCAGGACCAACTGGACATTGAATTATCTCGTAGCCAATTTGAAGAGGTCAGAGACAATAAACTCTATCTTGTTCAGGAT
CAGAAACCCATAGCCATTGGATTGGCTAAAGGGGGAGATATCCGAAAGACAGATGCGACTGGCCGTGGCTATCAACCGAT
GATAGACGGAGTCGAATCCGCCTTGATTGAAAAAAGAGGGGATTTGGTGTCTATTCAACTTCGCTTTGCAGAAGGATTAG
AAAGGGAGGTGGTCTACCGTGTGGTGGAAAAGGATAAAAAAGAAGCAGATTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	58.333	96	0.56
comGF/cglF	Streptococcus pneumoniae D39	58.333	96	0.56
comGF/cglF	Streptococcus pneumoniae R6	58.333	96	0.56
comGF/cglF	Streptococcus pneumoniae TIGR4	58.333	96	0.56
comGF/cglF	Streptococcus mitis SK321	56.835	92.667	0.527
comGF/cglF	Streptococcus mitis NCTC 12261	56.115	92.667	0.52
comYF	Streptococcus mutans UA159	41.379	96.667	0.4
comYF	Streptococcus mutans UA140	41.379	96.667	0.4
comGF	Lactococcus lactis subsp. cremoris KW2	39.855	92	0.367