Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I872_RS09745 Genome accession   NC_021175
Coordinates   1976620..1977561 (-) Length   313 a.a.
NCBI ID   WP_015605921.1    Uniprot ID   -
Organism   Streptococcus cristatus AS 1.3089     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1971620..1982561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS09710 (I872_09720) comYH 1972834..1973799 (-) 966 WP_015605914.1 class I SAM-dependent methyltransferase Machinery gene
  I872_RS09715 (I872_09725) comGG 1973880..1974287 (-) 408 WP_015605915.1 competence type IV pilus minor pilin ComGG -
  I872_RS09720 (I872_09730) comGF/cglF 1974268..1974705 (-) 438 WP_015605916.1 competence type IV pilus minor pilin ComGF Machinery gene
  I872_RS09725 (I872_09735) comGE/cglE 1974689..1974958 (-) 270 WP_015605917.1 competence type IV pilus minor pilin ComGE Machinery gene
  I872_RS09730 (I872_09740) comYD 1974948..1975382 (-) 435 WP_041826842.1 competence type IV pilus minor pilin ComGD Machinery gene
  I872_RS09735 (I872_09745) comYC 1975342..1975659 (-) 318 WP_015605919.1 competence type IV pilus major pilin ComGC Machinery gene
  I872_RS09740 (I872_09750) comYB 1975656..1976672 (-) 1017 WP_015605920.1 competence type IV pilus assembly protein ComGB Machinery gene
  I872_RS09745 (I872_09755) comYA 1976620..1977561 (-) 942 WP_015605921.1 competence type IV pilus ATPase ComGA Machinery gene
  I872_RS09750 (I872_09760) - 1977646..1978017 (-) 372 WP_015605922.1 DUF1033 family protein -
  I872_RS09755 - 1978152..1979420 (-) 1269 WP_041826843.1 CapA family protein -
  I872_RS09760 (I872_09770) comW 1979663..1979890 (-) 228 WP_015605924.1 sigma(X)-activator ComW -
  I872_RS09765 (I872_09775) - 1980064..1981500 (-) 1437 WP_015605925.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35856.00 Da        Isoelectric Point: 6.1691

>NTDB_id=58487 I872_RS09745 WP_015605921.1 1976620..1977561(-) (comYA) [Streptococcus cristatus AS 1.3089]
MVQKIAKEMIQLARQEAAQDIYLIPKSSCYELYMRVGDERRFIQTYDFDLLSSVISHFKFVSGMNVGEKRRSQLGSCDYD
CGDVTVSLRLSTVGDYRGYESLVIRLLHDEERELRFWFDNLPDLRKKVNSRGLYLFSGPVGSGKTTLMHQLAQMRFGQQQ
VMSIEDPVEIKQENMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDQETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVIDFVNQDYQKHEASLWNQQIDQLFADGHITADQRQAEKIIYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=58487 I872_RS09745 WP_015605921.1 1976620..1977561(-) (comYA) [Streptococcus cristatus AS 1.3089]
ATGGTTCAAAAAATTGCAAAGGAAATGATTCAATTGGCCAGGCAGGAAGCGGCCCAAGATATCTATCTGATTCCCAAGAG
TTCCTGCTATGAGCTTTATATGCGGGTGGGGGATGAGCGGCGTTTTATTCAGACCTATGATTTTGATTTACTGTCGTCAG
TCATCAGCCATTTTAAGTTTGTCTCGGGCATGAATGTTGGAGAGAAGAGGCGCAGCCAGCTAGGCTCCTGCGATTATGAT
TGTGGAGATGTGACGGTCTCGCTTCGTCTATCAACTGTCGGCGATTACCGTGGCTATGAGAGTCTGGTGATTCGGCTCTT
ACACGATGAGGAGCGTGAGTTGCGTTTCTGGTTTGACAATCTGCCTGATCTTCGTAAAAAAGTAAATTCTCGCGGCCTTT
ATCTGTTTTCAGGGCCAGTTGGCAGTGGAAAGACGACGCTGATGCACCAGCTGGCTCAGATGAGATTTGGGCAGCAACAG
GTCATGTCTATCGAAGACCCTGTTGAAATCAAGCAGGAAAACATGCTCCAGCTTCAACTGAATGAAACCATCGGCATGAC
CTACGACAGCCTCATCAAGCTATCTCTACGTCACCGACCAGATCTCTTGATTATCGGTGAAATCCGCGACCAAGAAACGG
CTCGTGCGGTGGTAAGGGCTAGTTTGACAGGCGCCACAGTCTTTTCAACTATCCATGCCAAGAGCATTCGCGGAGTGTAT
GAGCGCCTGCTGGAGCTGGGTGTCAGTGAGGACGAGCTGCGCATGGTGTTACAGGGCGTTTGTTATCAGCGCTTAATCGG
GGGAGGAGGTGTGATCGACTTTGTCAACCAAGACTATCAAAAGCACGAAGCCAGTCTCTGGAACCAGCAGATTGACCAGC
TTTTTGCAGATGGACATATCACAGCTGATCAAAGGCAGGCGGAAAAAATTATCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

79.355

99.042

0.786
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.441

100

0.744
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

73.482

100

0.735
  comGA/cglA/cilD Streptococcus pneumoniae D39

73.482

100

0.735
  comGA/cglA/cilD Streptococcus pneumoniae R6

73.482

100

0.735
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

73.482

100

0.735
  comYA Streptococcus mutans UA159

67.628

99.681

0.674
  comYA Streptococcus mutans UA140

67.628

99.681

0.674
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

99.042

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

55.769

99.681

0.556
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

88.498

0.364

Multiple sequence alignment