Detailed information NTG0058481

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: I872_RS09710
• Genome accession: NC_021175
• Coordinates: 1972834..1973799 (-)
• Length: 321 a.a.
• NCBI ID: WP_015605914.1
• Uniprot ID: A0A512AE28
• Organism: Streptococcus cristatus AS 1.3089
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1967834..1978799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I872_RS09695 (I872_09705)	pbp2a	1967859..1970081 (-)	2223	WP_015605911.1	penicillin-binding protein PBP2A	-
I872_RS09700 (I872_09710)	-	1970233..1971120 (+)	888	WP_041826841.1	RluA family pseudouridine synthase	-
I872_RS09705 (I872_09715)	-	1971602..1972798 (-)	1197	Protein_1906	acetate kinase	-
I872_RS09710 (I872_09720)	comYH	1972834..1973799 (-)	966	WP_015605914.1	class I SAM-dependent methyltransferase	Machinery gene
I872_RS09715 (I872_09725)	comGG	1973880..1974287 (-)	408	WP_015605915.1	competence type IV pilus minor pilin ComGG	-
I872_RS09720 (I872_09730)	comGF/cglF	1974268..1974705 (-)	438	WP_015605916.1	competence type IV pilus minor pilin ComGF	Machinery gene
I872_RS09725 (I872_09735)	comGE/cglE	1974689..1974958 (-)	270	WP_015605917.1	competence type IV pilus minor pilin ComGE	Machinery gene
I872_RS09730 (I872_09740)	comYD	1974948..1975382 (-)	435	WP_041826842.1	competence type IV pilus minor pilin ComGD	Machinery gene
I872_RS09735 (I872_09745)	comYC	1975342..1975659 (-)	318	WP_015605919.1	competence type IV pilus major pilin ComGC	Machinery gene
I872_RS09740 (I872_09750)	comYB	1975656..1976672 (-)	1017	WP_015605920.1	competence type IV pilus assembly protein ComGB	Machinery gene
I872_RS09745 (I872_09755)	comYA	1976620..1977561 (-)	942	WP_015605921.1	competence type IV pilus ATPase ComGA	Machinery gene
I872_RS09750 (I872_09760)	-	1977646..1978017 (-)	372	WP_015605922.1	DUF1033 family protein	-

Sequence

Protein

• Length: 321 a.a.
• Molecular weight: 36601.63 Da
• Isoelectric Point: 4.8000

>NTDB_id=58481 I872_RS09710 WP_015605914.1 1972834..1973799(-) (comYH) [Streptococcus cristatus AS 1.3089]
MKFEKIERAFHLLLENVQNIQNALGTNFYDALIEQNGIYLDGDTDLQEILKNNDKLRALHLTKEEWRRAYQFIFMKASQT
EPLQANHQFTPDSVGFLLSFLIDQLAQDERVDLLEIGSGTGNLAETLLNHTQKNMDYLGLEIDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDLIVSDLPVGYYPDDAVAARYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNNLLTSPQ
SHLLKKWLLSSAQLLAMISLPEKIFASRQSAKTLFVLRKQGESDIQPFIYPLQDLQSQDEILKFRESFQNWVKVSEIRTN
F

Nucleotide

• Length: 966 bp

>NTDB_id=58481 I872_RS09710 WP_015605914.1 1972834..1973799(-) (comYH) [Streptococcus cristatus AS 1.3089]
ATGAAATTTGAAAAAATAGAACGAGCTTTTCACCTGCTTTTAGAAAACGTGCAAAATATCCAAAATGCGCTGGGAACTAA
TTTTTATGATGCTTTGATTGAGCAAAATGGGATTTATCTGGATGGAGATACGGACTTACAAGAAATTCTGAAAAACAATG
ACAAGCTTCGTGCCCTGCATTTGACCAAGGAAGAGTGGCGGCGGGCTTATCAGTTTATTTTTATGAAGGCTTCTCAGACA
GAGCCGCTTCAAGCCAATCATCAGTTCACACCTGATTCGGTCGGCTTCTTGCTGAGTTTTTTGATTGACCAGTTGGCACA
AGACGAGAGAGTTGATTTGCTGGAGATCGGCAGTGGAACAGGTAATTTGGCGGAGACTCTGCTCAACCACACACAAAAAA
ATATGGATTATCTAGGCCTAGAAATTGACGACTTACTGATTGATTTATCTGCCAGTATTGCTGAAGTCATGAATTCCAAG
GCACACTTTGCTCAAGGAGATGCGGTGCGGCCTCAGGTTCTGAAAGAAAGCGACTTGATTGTCAGTGATTTACCAGTGGG
TTATTATCCCGATGATGCAGTAGCTGCTCGCTATGAGGTTGCTAGCCCAGATGAGCATACCTACGCCCATCATCTCTTGA
TGGAGCAGTCGCTAAAATATTTGAAACCGGGAGGCTATGCTATCTTTCTTGCACCAAATAATCTGCTGACAAGCCCTCAG
AGTCACCTGCTGAAAAAATGGTTGCTTTCTAGCGCCCAGCTCTTGGCAATGATTTCCCTGCCAGAGAAGATTTTCGCAAG
CCGTCAGAGTGCCAAGACACTATTTGTCTTAAGGAAACAAGGCGAATCAGACATCCAGCCTTTTATCTACCCTTTGCAGG
ACCTGCAAAGTCAGGATGAAATCTTGAAGTTTCGTGAAAGTTTTCAAAACTGGGTCAAAGTTAGTGAAATTCGAACAAAT
TTCTGA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-282)

3D structure

• AlphaFold DB: A0A512AE28

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	58.521	96.885	0.567
comYH	Streptococcus mutans UA140	58.521	96.885	0.567