Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   I872_RS09740 Genome accession   NC_021175
Coordinates   1975656..1976672 (-) Length   338 a.a.
NCBI ID   WP_015605920.1    Uniprot ID   -
Organism   Streptococcus cristatus AS 1.3089     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1970656..1981672
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS09705 (I872_09715) - 1971602..1972798 (-) 1197 Protein_1906 acetate kinase -
  I872_RS09710 (I872_09720) comYH 1972834..1973799 (-) 966 WP_015605914.1 class I SAM-dependent methyltransferase Machinery gene
  I872_RS09715 (I872_09725) comGG 1973880..1974287 (-) 408 WP_015605915.1 competence type IV pilus minor pilin ComGG -
  I872_RS09720 (I872_09730) comGF/cglF 1974268..1974705 (-) 438 WP_015605916.1 competence type IV pilus minor pilin ComGF Machinery gene
  I872_RS09725 (I872_09735) comGE/cglE 1974689..1974958 (-) 270 WP_015605917.1 competence type IV pilus minor pilin ComGE Machinery gene
  I872_RS09730 (I872_09740) comYD 1974948..1975382 (-) 435 WP_041826842.1 competence type IV pilus minor pilin ComGD Machinery gene
  I872_RS09735 (I872_09745) comYC 1975342..1975659 (-) 318 WP_015605919.1 competence type IV pilus major pilin ComGC Machinery gene
  I872_RS09740 (I872_09750) comYB 1975656..1976672 (-) 1017 WP_015605920.1 competence type IV pilus assembly protein ComGB Machinery gene
  I872_RS09745 (I872_09755) comYA 1976620..1977561 (-) 942 WP_015605921.1 competence type IV pilus ATPase ComGA Machinery gene
  I872_RS09750 (I872_09760) - 1977646..1978017 (-) 372 WP_015605922.1 DUF1033 family protein -
  I872_RS09755 - 1978152..1979420 (-) 1269 WP_041826843.1 CapA family protein -
  I872_RS09760 (I872_09770) comW 1979663..1979890 (-) 228 WP_015605924.1 sigma(X)-activator ComW -
  I872_RS09765 (I872_09775) - 1980064..1981500 (-) 1437 WP_015605925.1 hypothetical protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38599.57 Da        Isoelectric Point: 9.0064

>NTDB_id=58486 I872_RS09740 WP_015605920.1 1975656..1976672(-) (comYB) [Streptococcus cristatus AS 1.3089]
MDISQLIKGRRKKLSTPKQKKIIELFRNLFTSGFHLAEIVDFLRRSALLEEIYVSEMRSGLAAGQSFSQIMKRLGFSDNV
VTQLSLSELHGNLNLSLGKIEDYLENLSKVRKKLVEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNMATQFIHYLPQIF
LGGVLVLGLLICSGWFYYRKSSKMGFFSCLAKFPFVGTLVRAYLTAYYAREWGNMIGQGLELSQIFLIMQDQPSQLFQEL
GRDLEAALGAGQGYAEKVGTYPFFKKELALIIEYGEVKSKLGDELELYAEKTWEEFFLRINRAMNLIQPLVFVFVALVIV
LLYAAMLLPIYQNMEIQL

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=58486 I872_RS09740 WP_015605920.1 1975656..1976672(-) (comYB) [Streptococcus cristatus AS 1.3089]
ATGGACATATCACAGCTGATCAAAGGCAGGCGGAAAAAATTATCTACGCCTAAGCAAAAGAAGATTATCGAGCTGTTTCG
TAATCTCTTTACCAGTGGTTTTCATTTGGCGGAGATTGTCGACTTCCTGCGCCGAAGTGCCCTTTTAGAAGAAATTTATG
TCTCAGAAATGCGTTCGGGTTTGGCTGCTGGCCAGTCGTTTTCGCAGATTATGAAGCGTTTGGGCTTTTCAGATAATGTG
GTCACCCAGCTGTCTTTATCAGAGCTGCATGGAAATCTAAATCTTAGTTTGGGTAAAATCGAAGATTATTTAGAAAATCT
TTCGAAAGTCCGTAAGAAATTGGTTGAGGTGGGGACTTATCCCTTGATGCTGCTTGGGTTTTTGGTGCTAATTATGCTGG
GCTTGCGCAACTACCTTCTGCCTCAGCTGGATAGTCAAAATATGGCCACTCAGTTCATTCATTATCTACCGCAAATCTTT
TTGGGAGGTGTTCTGGTGCTGGGCTTGCTGATTTGCAGTGGCTGGTTCTATTATCGCAAGAGCTCTAAGATGGGATTTTT
CAGTTGTTTGGCCAAGTTTCCTTTTGTTGGCACCTTAGTGCGGGCCTATCTGACAGCCTACTATGCGCGTGAATGGGGCA
ATATGATTGGGCAAGGGCTGGAATTGAGTCAGATTTTTCTCATCATGCAGGACCAGCCGTCTCAGCTCTTTCAGGAGCTG
GGGCGAGACTTGGAGGCGGCTCTAGGTGCAGGTCAGGGTTATGCCGAGAAGGTCGGGACCTATCCCTTCTTTAAGAAAGA
GTTGGCCTTAATCATTGAATACGGCGAGGTCAAGTCCAAGTTGGGCGACGAATTGGAGCTATATGCCGAAAAGACTTGGG
AAGAGTTTTTCCTGAGAATCAATCGTGCCATGAATTTGATTCAGCCTCTCGTCTTTGTCTTTGTCGCCCTCGTGATCGTT
TTACTTTATGCAGCCATGTTGCTGCCAATTTATCAGAATATGGAGATTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

70.92

99.704

0.707
  comGB/cglB Streptococcus mitis NCTC 12261

67.56

99.408

0.672
  comGB/cglB Streptococcus pneumoniae Rx1

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae D39

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae TIGR4

67.262

99.408

0.669
  comGB/cglB Streptococcus pneumoniae R6

67.262

99.408

0.669
  comGB/cglB Streptococcus mitis SK321

67.262

99.408

0.669
  comYB Streptococcus mutans UA140

60.883

93.787

0.571
  comYB Streptococcus mutans UA159

60.568

93.787

0.568
  comGB Lactococcus lactis subsp. cremoris KW2

49.701

98.817

0.491

Multiple sequence alignment