Detailed information NTG0058200

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: SPN034183_RS09755
• Genome accession: NC_021028
• Coordinates: 1795553..1796032 (-)
• Length: 159 a.a.
• NCBI ID: WP_000588866.1
• Uniprot ID: A0A6C7J1A1
• Organism: Streptococcus pneumoniae SPN034183
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1790553..1801032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034183_RS09755 (SPN034183_17690)	comX/comX2	1795553..1796032 (-)	480	WP_000588866.1	sigma-70 family RNA polymerase sigma factor	Regulator
SPN034183_RS09760 (SPN034183_17700)	nusG	1796154..1796690 (-)	537	WP_000376736.1	transcription termination/antitermination protein NusG	-
SPN034183_RS09765 (SPN034183_17710)	secE	1796745..1796921 (-)	177	WP_001210991.1	preprotein translocase subunit SecE	-
SPN034183_RS09770 (SPN034183_17720)	rpmG	1796931..1797083 (-)	153	WP_001809375.1	50S ribosomal protein L33	-
SPN034183_RS09775 (SPN034183_17730)	pbp2a	1797136..1799331 (-)	2196	WP_000762627.1	penicillin-binding protein PBP2A	-
SPN034183_RS09780 (SPN034183_17740)	-	1799418..1800293 (+)	876	WP_001809376.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19845.46 Da
• Isoelectric Point: 7.3797

>NTDB_id=58200 SPN034183_RS09755 WP_000588866.1 1795553..1796032(-) (comX/comX2) [Streptococcus pneumoniae SPN034183]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=58200 SPN034183_RS09755 WP_000588866.1 1795553..1796032(-) (comX/comX2) [Streptococcus pneumoniae SPN034183]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGCAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6C7J1A1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae Rx1	98.742	100	0.987
comX/comX2	Streptococcus pneumoniae D39	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae D39	98.742	100	0.987
comX/comX2	Streptococcus pneumoniae R6	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae R6	98.742	100	0.987
comX/comX2	Streptococcus pneumoniae TIGR4	98.113	100	0.981
comX/comX1	Streptococcus pneumoniae TIGR4	98.113	100	0.981
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.195	100	0.912
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.195	100	0.912
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.308	100	0.893
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	89.241	99.371	0.887
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comX/sigX	Streptococcus suis D9	45.695	94.969	0.434
comX/sigX	Streptococcus suis isolate S10	45.695	94.969	0.434
comX/sigX	Streptococcus suis P1/7	45.695	94.969	0.434
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX	Streptococcus sobrinus strain NIDR 6715-7	38.926	93.711	0.365