Detailed information NTG0558755

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: KCL43_RS00720
• Genome accession: NZ_CP073275
• Coordinates: 127586..127909 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. zooepidemicus strain IN-6992
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122586..132909

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCL43_RS10465	-	122665..122781 (+)	117	WP_231145532.1	hypothetical protein	-
KCL43_RS00700 (KCL43_00700)	-	122846..124849 (+)	2004	WP_165623678.1	DUF1430 domain-containing protein	-
KCL43_RS00705 (KCL43_00705)	-	124851..125498 (+)	648	WP_115266548.1	ATP-binding cassette domain-containing protein	-
KCL43_RS00710 (KCL43_00710)	comGA/cglA	125680..126618 (+)	939	WP_115267238.1	competence type IV pilus ATPase ComGA	Machinery gene
KCL43_RS00715 (KCL43_00715)	comYB	126551..127585 (+)	1035	WP_228294477.1	competence type IV pilus assembly protein ComGB	Machinery gene
KCL43_RS00720 (KCL43_00720)	comGC/cglC	127586..127909 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
KCL43_RS00725 (KCL43_00725)	comGD	127887..128312 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
KCL43_RS00730 (KCL43_00730)	comGE	128317..128559 (+)	243	WP_207618698.1	competence type IV pilus minor pilin ComGE	-
KCL43_RS00735 (KCL43_00735)	comYF	128546..128980 (+)	435	WP_111677651.1	competence type IV pilus minor pilin ComGF	Machinery gene
KCL43_RS00740 (KCL43_00740)	comGG	128958..129320 (+)	363	WP_111677652.1	competence type IV pilus minor pilin ComGG	-
KCL43_RS00745 (KCL43_00745)	-	129387..130728 (+)	1342	Protein_113	IS3 family transposase	-
KCL43_RS00750 (KCL43_00750)	comYH	130813..131766 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=558755 KCL43_RS00720 WP_012514782.1 127586..127909(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=558755 KCL43_RS00720 WP_012514782.1 127586..127909(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTATTAAT
CATTAGTGTTTTAATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCAG
TGGTAAAGCTAGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364