Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   KCL43_RS00710 Genome accession   NZ_CP073275
Coordinates   125680..126618 (+) Length   312 a.a.
NCBI ID   WP_115267238.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain IN-6992     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120680..131618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCL43_RS00690 (KCL43_00690) - 121041..122273 (+) 1233 WP_014622136.1 hypothetical protein -
  KCL43_RS10465 - 122665..122781 (+) 117 WP_231145532.1 hypothetical protein -
  KCL43_RS00700 (KCL43_00700) - 122846..124849 (+) 2004 WP_165623678.1 DUF1430 domain-containing protein -
  KCL43_RS00705 (KCL43_00705) - 124851..125498 (+) 648 WP_115266548.1 ATP-binding cassette domain-containing protein -
  KCL43_RS00710 (KCL43_00710) comGA/cglA 125680..126618 (+) 939 WP_115267238.1 competence type IV pilus ATPase ComGA Machinery gene
  KCL43_RS00715 (KCL43_00715) comYB 126551..127585 (+) 1035 WP_228294477.1 competence type IV pilus assembly protein ComGB Machinery gene
  KCL43_RS00720 (KCL43_00720) comGC/cglC 127586..127909 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  KCL43_RS00725 (KCL43_00725) comGD 127887..128312 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  KCL43_RS00730 (KCL43_00730) comGE 128317..128559 (+) 243 WP_207618698.1 competence type IV pilus minor pilin ComGE -
  KCL43_RS00735 (KCL43_00735) comYF 128546..128980 (+) 435 WP_111677651.1 competence type IV pilus minor pilin ComGF Machinery gene
  KCL43_RS00740 (KCL43_00740) comGG 128958..129320 (+) 363 WP_111677652.1 competence type IV pilus minor pilin ComGG -
  KCL43_RS00745 (KCL43_00745) - 129387..130728 (+) 1342 Protein_113 IS3 family transposase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35307.51 Da        Isoelectric Point: 6.8988

>NTDB_id=558753 KCL43_RS00710 WP_115267238.1 125680..126618(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAIVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANWWNQQIDQLLAEGHLNSRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=558753 KCL43_RS00710 WP_115267238.1 125680..126618(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAAGCTATGAGCTTTTGATGAGGATAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATAGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAACTGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.359

0.683
  comYA Streptococcus mutans UA159

63.666

99.679

0.635
  comYA Streptococcus mutans UA140

63.666

99.679

0.635
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA Lactococcus lactis subsp. cremoris KW2

53.055

99.679

0.529
  comGA Latilactobacillus sakei subsp. sakei 23K

39.931

92.308

0.369