Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   J7U23_RS09035 Genome accession   NZ_CP072435
Coordinates   1748487..1749428 (-) Length   313 a.a.
NCBI ID   WP_372589905.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24736     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1743487..1754428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U23_RS08995 (J7U23_08890) - 1743563..1744756 (-) 1194 WP_084831204.1 acetate kinase -
  J7U23_RS09000 (J7U23_08895) comYH 1744812..1745768 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  J7U23_RS09005 (J7U23_08900) comGG 1745813..1746130 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG -
  J7U23_RS09010 (J7U23_08905) comYF 1746108..1746545 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7U23_RS09015 (J7U23_08910) comGE 1746529..1746822 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  J7U23_RS09020 (J7U23_08915) comYD 1746794..1747222 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7U23_RS09025 (J7U23_08920) comYC 1747182..1747508 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7U23_RS09030 (J7U23_08925) comYB 1747505..1748605 (-) 1101 WP_271307389.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7U23_RS09035 (J7U23_08930) comYA 1748487..1749428 (-) 942 WP_372589905.1 competence type IV pilus ATPase ComGA Machinery gene
  J7U23_RS09040 (J7U23_08935) - 1749509..1749871 (-) 363 WP_372433446.1 DUF1033 family protein -
  J7U23_RS09045 (J7U23_08940) rpoC 1750030..1753668 (-) 3639 WP_011681690.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35465.67 Da        Isoelectric Point: 6.3927

>NTDB_id=552952 J7U23_RS09035 WP_372589905.1 1748487..1749428(-) (comYA) [Streptococcus thermophilus strain S24736]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGLCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQTIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=552952 J7U23_RS09035 WP_372589905.1 1748487..1749428(-) (comYA) [Streptococcus thermophilus strain S24736]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTTATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCTATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGACGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTCTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

63.259

100

0.633
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.538

99.681

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377