Detailed information NTG0552951

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: J7U23_RS09030
• Genome accession: NZ_CP072435
• Coordinates: 1747505..1748605 (-)
• Length: 366 a.a.
• NCBI ID: WP_271307389.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24736
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1742505..1753605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS08990 (J7U23_08885)	-	1743117..1743314 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
J7U23_RS08995 (J7U23_08890)	-	1743563..1744756 (-)	1194	WP_084831204.1	acetate kinase	-
J7U23_RS09000 (J7U23_08895)	comYH	1744812..1745768 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
J7U23_RS09005 (J7U23_08900)	comGG	1745813..1746130 (-)	318	WP_082309152.1	competence type IV pilus minor pilin ComGG	-
J7U23_RS09010 (J7U23_08905)	comYF	1746108..1746545 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7U23_RS09015 (J7U23_08910)	comGE	1746529..1746822 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7U23_RS09020 (J7U23_08915)	comYD	1746794..1747222 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7U23_RS09025 (J7U23_08920)	comYC	1747182..1747508 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7U23_RS09030 (J7U23_08925)	comYB	1747505..1748605 (-)	1101	WP_271307389.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7U23_RS09035 (J7U23_08930)	comYA	1748487..1749428 (-)	942	WP_372589905.1	competence type IV pilus ATPase ComGA	Machinery gene
J7U23_RS09040 (J7U23_08935)	-	1749509..1749871 (-)	363	WP_372433446.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41806.92 Da
• Isoelectric Point: 10.1084

>NTDB_id=552951 J7U23_RS09030 WP_271307389.1 1747505..1748605(-) (comYB) [Streptococcus thermophilus strain S24736]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRHSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=552951 J7U23_RS09030 WP_271307389.1 1747505..1748605(-) (comYB) [Streptococcus thermophilus strain S24736]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACATTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	50.877	93.443	0.475
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413