Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I6K87_RS06485 Genome accession   NZ_CP069892
Coordinates   1323014..1323955 (-) Length   313 a.a.
NCBI ID   WP_003028470.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1318014..1328955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS06445 (I6K87_06445) - 1318088..1319287 (-) 1200 WP_003028479.1 acetate kinase -
  I6K87_RS06450 (I6K87_06450) comYH 1319334..1320287 (-) 954 WP_003039058.1 class I SAM-dependent methyltransferase Machinery gene
  I6K87_RS06455 (I6K87_06455) comGG 1320355..1320681 (-) 327 WP_259334802.1 competence type IV pilus minor pilin ComGG -
  I6K87_RS06460 (I6K87_06460) comGF/cglF 1320662..1321099 (-) 438 WP_204982485.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6K87_RS06465 (I6K87_06465) comGE/cglE 1321083..1321376 (-) 294 WP_126406234.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6K87_RS06470 (I6K87_06470) comYD 1321348..1321776 (-) 429 WP_037566697.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6K87_RS06475 (I6K87_06475) comYC 1321736..1322053 (-) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  I6K87_RS06480 (I6K87_06480) comYB 1322050..1323072 (-) 1023 WP_180363191.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6K87_RS06485 (I6K87_06485) comYA 1323014..1323955 (-) 942 WP_003028470.1 competence type IV pilus ATPase ComGA Machinery gene
  I6K87_RS06490 (I6K87_06490) - 1324025..1324390 (-) 366 WP_022525291.1 DUF1033 family protein -
  I6K87_RS06495 (I6K87_06495) glnA 1324575..1325921 (-) 1347 WP_022525292.1 type I glutamate--ammonia ligase -
  I6K87_RS06500 (I6K87_06500) - 1325960..1326319 (-) 360 WP_003028467.1 MerR family transcriptional regulator -
  I6K87_RS06505 (I6K87_06505) - 1326396..1326926 (-) 531 WP_003028466.1 FUSC family protein -
  I6K87_RS09975 (I6K87_06510) - 1327077..1327759 (-) 683 Protein_1277 COG3942 and LysM peptidoglycan-binding domain-containing protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35806.02 Da        Isoelectric Point: 6.0555

>NTDB_id=537268 I6K87_RS06485 WP_003028470.1 1323014..1323955(-) (comYA) [Streptococcus anginosus strain FDAARGOS_1357]
MVQNIAQAIICQAKEEQAQDIYVVPKENMYELYMRIGDERRFIQQYAFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKQTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFAGQQ
IMSIEDPVEIKQPSMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDGETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=537268 I6K87_RS06485 WP_003028470.1 1323014..1323955(-) (comYA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGGTTCAAAATATTGCACAGGCTATTATTTGCCAAGCTAAGGAAGAACAGGCTCAGGATATTTACGTTGTTCCAAAAGA
AAATATGTATGAGCTATACATGCGAATTGGCGATGAACGGCGTTTTATACAACAGTATGCATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTCAAGTTTACCGCTGGAATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGACAAGCAAACGTCACTACGACTGTCAACAGTAGGGGATTATCGTGGATATGAAAGTCTGGTGATTCGTTTATT
ACATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAGCGAGGGCTTT
ATCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACAACTCTCATGCACCAACTCGCCCAAGAGCGTTTTGCTGGTCAGCAA
ATCATGTCCATTGAAGACCCTGTTGAAATCAAGCAGCCTAGCATGTTACAGTTGCAATTAAATGAAGCGATTGGTTTGAC
TTATGAAAATTTGATTAAACTTTCTCTACGGCACCGACCGGATTTGCTAATCATCGGAGAAATTCGAGATGGGGAGACAG
CACGGGCTGTTGTCCGAGCTAGCTTGACAGGAGTGACTGTCTTTTCAACCATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGTTGGAATTAGGAGTGACAGAAGCCGAGCTGAAAATTGTCTTGCAAGGGATTTGTTACCAACGTTTAATTGC
AAAAGGAGGAATAGTGGATTTTGTCAGTGAAAAGTATCAAGAACACGAGCCAATCGACTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAACAAGCAGAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.952

99.361

0.645
  comYA Streptococcus mutans UA140

64.952

99.361

0.645
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

42.857

84.984

0.364