Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   IGS65_RS08710 Genome accession   NZ_CP066294
Coordinates   1800338..1801279 (+) Length   313 a.a.
NCBI ID   WP_192072412.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1795338..1806279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS08700 (IGS65_008700) rpoC 1796067..1799696 (+) 3630 WP_002295833.1 DNA-directed RNA polymerase subunit beta' -
  IGS65_RS08705 (IGS65_008705) - 1799823..1800206 (+) 384 WP_002264248.1 DUF1033 family protein -
  IGS65_RS08710 (IGS65_008710) comYA 1800338..1801279 (+) 942 WP_192072412.1 competence type IV pilus ATPase ComGA Machinery gene
  IGS65_RS08715 (IGS65_008715) comYB 1801215..1802246 (+) 1032 WP_280517816.1 competence type IV pilus assembly protein ComGB Machinery gene
  IGS65_RS08720 (IGS65_008720) comYC 1802246..1802560 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  IGS65_RS08725 (IGS65_008725) comYD 1802547..1802951 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  IGS65_RS08730 (IGS65_008730) comYE 1802923..1803216 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  IGS65_RS08735 (IGS65_008735) comYF 1803203..1803637 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  IGS65_RS08740 (IGS65_008740) comYG 1803615..1804004 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  IGS65_RS08745 (IGS65_008745) comYH 1804059..1805012 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  IGS65_RS08750 (IGS65_008750) - 1805071..1806270 (+) 1200 WP_002263443.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35721.06 Da        Isoelectric Point: 8.0347

>NTDB_id=519155 IGS65_RS08710 WP_192072412.1 1800338..1801279(+) (comYA) [Streptococcus mutans strain 27-3]
MVQKLGRKIIAEAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSLDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFETK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=519155 IGS65_RS08710 WP_192072412.1 1800338..1801279(+) (comYA) [Streptococcus mutans strain 27-3]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCGAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGTGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTTTGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCAGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGAGACCAAA
CAGGTAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGCATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

99.681

100

0.997
  comYA Streptococcus mutans UA140

99.361

100

0.994
  comYA Streptococcus gordonii str. Challis substr. CH1

67.093

100

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.346

99.681

0.661
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

99.361

0.655
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521