Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   IGS65_RS08715 Genome accession   NZ_CP066294
Coordinates   1801215..1802246 (+) Length   343 a.a.
NCBI ID   WP_280517816.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1796215..1807246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS08705 (IGS65_008705) - 1799823..1800206 (+) 384 WP_002264248.1 DUF1033 family protein -
  IGS65_RS08710 (IGS65_008710) comYA 1800338..1801279 (+) 942 WP_192072412.1 competence type IV pilus ATPase ComGA Machinery gene
  IGS65_RS08715 (IGS65_008715) comYB 1801215..1802246 (+) 1032 WP_280517816.1 competence type IV pilus assembly protein ComGB Machinery gene
  IGS65_RS08720 (IGS65_008720) comYC 1802246..1802560 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  IGS65_RS08725 (IGS65_008725) comYD 1802547..1802951 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  IGS65_RS08730 (IGS65_008730) comYE 1802923..1803216 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  IGS65_RS08735 (IGS65_008735) comYF 1803203..1803637 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  IGS65_RS08740 (IGS65_008740) comYG 1803615..1804004 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  IGS65_RS08745 (IGS65_008745) comYH 1804059..1805012 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  IGS65_RS08750 (IGS65_008750) - 1805071..1806270 (+) 1200 WP_002263443.1 acetate kinase -
  IGS65_RS08755 (IGS65_008755) - 1806815..1807060 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39872.47 Da        Isoelectric Point: 9.5205

>NTDB_id=519156 IGS65_RS08715 WP_280517816.1 1801215..1802246(+) (comYB) [Streptococcus mutans strain 27-3]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQIERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMERALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=519156 IGS65_RS08715 WP_280517816.1 1801215..1802246(+) (comYB) [Streptococcus mutans strain 27-3]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAAATTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGCTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAGGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.417

100

0.994
  comYB Streptococcus mutans UA140

98.834

100

0.988
  comYB Streptococcus gordonii str. Challis substr. CH1

59.767

100

0.598
  comGB/cglB Streptococcus mitis NCTC 12261

58.112

98.834

0.574
  comGB/cglB Streptococcus mitis SK321

56.25

97.959

0.551
  comGB/cglB Streptococcus pneumoniae Rx1

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae D39

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae R6

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae TIGR4

55.655

97.959

0.545
  comGB Lactococcus lactis subsp. cremoris KW2

51.335

98.251

0.504