Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   IGS65_RS08730 Genome accession   NZ_CP066294
Coordinates   1802923..1803216 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1797923..1808216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS08705 (IGS65_008705) - 1799823..1800206 (+) 384 WP_002264248.1 DUF1033 family protein -
  IGS65_RS08710 (IGS65_008710) comYA 1800338..1801279 (+) 942 WP_192072412.1 competence type IV pilus ATPase ComGA Machinery gene
  IGS65_RS08715 (IGS65_008715) comYB 1801215..1802246 (+) 1032 WP_280517816.1 competence type IV pilus assembly protein ComGB Machinery gene
  IGS65_RS08720 (IGS65_008720) comYC 1802246..1802560 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  IGS65_RS08725 (IGS65_008725) comYD 1802547..1802951 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  IGS65_RS08730 (IGS65_008730) comYE 1802923..1803216 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  IGS65_RS08735 (IGS65_008735) comYF 1803203..1803637 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  IGS65_RS08740 (IGS65_008740) comYG 1803615..1804004 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  IGS65_RS08745 (IGS65_008745) comYH 1804059..1805012 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  IGS65_RS08750 (IGS65_008750) - 1805071..1806270 (+) 1200 WP_002263443.1 acetate kinase -
  IGS65_RS08755 (IGS65_008755) - 1806815..1807060 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  IGS65_RS08760 (IGS65_008760) - 1807029..1807469 (+) 441 WP_002263445.1 hypothetical protein -
  IGS65_RS08765 (IGS65_008765) - 1807522..1808184 (+) 663 WP_002263446.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=519159 IGS65_RS08730 WP_002263439.1 1802923..1803216(+) (comYE) [Streptococcus mutans strain 27-3]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=519159 IGS65_RS08730 WP_002263439.1 1802923..1803216(+) (comYE) [Streptococcus mutans strain 27-3]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412