Detailed information NTG0519158

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: IGS65_RS08725
• Genome accession: NZ_CP066294
• Coordinates: 1802547..1802951 (+)
• Length: 134 a.a.
• NCBI ID: WP_002263438.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain 27-3
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1797547..1807951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS08705 (IGS65_008705)	-	1799823..1800206 (+)	384	WP_002264248.1	DUF1033 family protein	-
IGS65_RS08710 (IGS65_008710)	comYA	1800338..1801279 (+)	942	WP_192072412.1	competence type IV pilus ATPase ComGA	Machinery gene
IGS65_RS08715 (IGS65_008715)	comYB	1801215..1802246 (+)	1032	WP_280517816.1	competence type IV pilus assembly protein ComGB	Machinery gene
IGS65_RS08720 (IGS65_008720)	comYC	1802246..1802560 (+)	315	WP_002263437.1	competence type IV pilus major pilin ComGC	Machinery gene
IGS65_RS08725 (IGS65_008725)	comYD	1802547..1802951 (+)	405	WP_002263438.1	competence type IV pilus minor pilin ComGD	Machinery gene
IGS65_RS08730 (IGS65_008730)	comYE	1802923..1803216 (+)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
IGS65_RS08735 (IGS65_008735)	comYF	1803203..1803637 (+)	435	WP_002263440.1	competence type IV pilus minor pilin ComGF	Machinery gene
IGS65_RS08740 (IGS65_008740)	comYG	1803615..1804004 (+)	390	WP_002263441.1	competence type IV pilus minor pilin ComGG	Machinery gene
IGS65_RS08745 (IGS65_008745)	comYH	1804059..1805012 (+)	954	WP_002264244.1	class I SAM-dependent methyltransferase	Machinery gene
IGS65_RS08750 (IGS65_008750)	-	1805071..1806270 (+)	1200	WP_002263443.1	acetate kinase	-
IGS65_RS08755 (IGS65_008755)	-	1806815..1807060 (+)	246	WP_002263444.1	helix-turn-helix transcriptional regulator	-
IGS65_RS08760 (IGS65_008760)	-	1807029..1807469 (+)	441	WP_002263445.1	hypothetical protein	-

Sequence

Protein

• Length: 134 a.a.
• Molecular weight: 15444.77 Da
• Isoelectric Point: 9.5619

>NTDB_id=519158 IGS65_RS08725 WP_002263438.1 1802547..1802951(+) (comYD) [Streptococcus mutans strain 27-3]
MSRIKAFTLIESLVTLAITSFLILSFSGSITQTFAKVEERLFFLSFEHLYRDTQKLSVYQRQDMTLILKSEYISNGVEVL
KIPKDVKLERNKTLHFDQAGGNSSLEKLVFQTSDEKRVTYQLYIGSGQYKKTES

Nucleotide

• Length: 405 bp

>NTDB_id=519158 IGS65_RS08725 WP_002263438.1 1802547..1802951(+) (comYD) [Streptococcus mutans strain 27-3]
ATGTCGCGAATTAAAGCTTTTACGCTTATAGAAAGTTTAGTGACTTTGGCAATTACTAGTTTTTTGATTTTAAGCTTTTC
AGGTAGTATAACTCAAACGTTTGCCAAAGTAGAAGAGCGTCTCTTTTTTCTTTCTTTTGAACATCTTTACCGTGACACGC
AAAAACTTAGTGTTTATCAAAGACAAGATATGACTTTAATATTAAAAAGCGAATATATCTCAAATGGTGTTGAAGTACTT
AAAATCCCTAAGGATGTCAAACTAGAGAGGAATAAAACTTTGCACTTTGATCAGGCAGGAGGAAATTCTTCTTTAGAAAA
ACTTGTTTTTCAAACATCTGATGAAAAAAGAGTTACTTATCAATTATATATAGGAAGTGGTCAGTATAAAAAAACAGAAA
GTTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (1-25)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus mutans UA140	100	100	1
comYD	Streptococcus mutans UA159	100	100	1
comYD	Streptococcus gordonii str. Challis substr. CH1	50.388	96.269	0.485
comGD/cglD	Streptococcus mitis NCTC 12261	49.612	96.269	0.478
comGD/cglD	Streptococcus pneumoniae Rx1	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae D39	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae R6	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae TIGR4	48.438	95.522	0.463
comGD/cglD	Streptococcus mitis SK321	48.438	95.522	0.463
comGD	Lactococcus lactis subsp. cremoris KW2	39.394	98.507	0.388