Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   I6I02_RS00120 Genome accession   NZ_CP066093
Coordinates   32960..33901 (+) Length   313 a.a.
NCBI ID   WP_060971595.1    Uniprot ID   A0AAW7PDY8
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 27960..38901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS00110 (I6I02_00110) rpoC 28716..32354 (+) 3639 WP_198463593.1 DNA-directed RNA polymerase subunit beta' -
  I6I02_RS00115 (I6I02_00115) - 32517..32879 (+) 363 WP_002887019.1 DUF1033 family protein -
  I6I02_RS00120 (I6I02_00120) comGA/cglA/cilD 32960..33901 (+) 942 WP_060971595.1 competence type IV pilus ATPase ComGA Machinery gene
  I6I02_RS00125 (I6I02_00125) comYB 33783..34883 (+) 1101 WP_198463594.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6I02_RS00130 (I6I02_00130) comYC 34880..35206 (+) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  I6I02_RS00135 (I6I02_00135) comYD 35166..35594 (+) 429 WP_269780043.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6I02_RS00140 (I6I02_00140) comGE 35626..35856 (+) 231 WP_051412000.1 competence type IV pilus minor pilin ComGE -
  I6I02_RS00145 (I6I02_00145) comYF 35843..36280 (+) 438 WP_037601472.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6I02_RS00150 (I6I02_00150) comGG 36258..36575 (+) 318 WP_041817287.1 competence type IV pilus minor pilin ComGG -
  I6I02_RS00155 (I6I02_00155) comYH 36620..37576 (+) 957 WP_013991262.1 class I SAM-dependent methyltransferase Machinery gene
  I6I02_RS00160 (I6I02_00160) - 37633..38826 (+) 1194 WP_003095894.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35257.23 Da        Isoelectric Point: 5.6687

>NTDB_id=517326 I6I02_RS00120 WP_060971595.1 32960..33901(+) (comGA/cglA/cilD) [Streptococcus salivarius strain FDAARGOS_1045]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGHLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=517326 I6I02_RS00120 WP_060971595.1 32960..33901(+) (comGA/cglA/cilD) [Streptococcus salivarius strain FDAARGOS_1045]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCAACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTACCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGTCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGACATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

63.259

100

0.633
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.218

99.681

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361